First of all, e2 rebounds after arimidex only because it's not a suicide inhibitor. It blocks aromatase but after some time it becomes inactive and lets it go free. There's no such problem with suicide inhibitors like aromasin or atd.
Biggest issue with AI is finding sweet spot. For whatever reason, every combination I've tried and trust me, I've tried a dozen made me either have bad skin, still bloated, low libido or whatever combination of those. I may speculate why it happens but it all comes down to the fact that it's really hard to fool your body.
When it comes to cholesterol it's not that simple. Overall, from studies I've read there are several conclusions:
- it's better to have lower ldl than higher regardless of everything else
- it's better to have lower triglycerides as it pretty much means your ldl particles are large
- it's better to have high hdl than lower
Larger particles are indeed better than smaller but still, when particles are of the same size it's better to have less of them.
For me, intermittent fasting or rather eating less frequent meals and fasting lowered my triglycerides significantly. I believe in abuse of omega3, like over 10g of pure omega3 per day. The risk and potential side effects are small and for whatever reason it makes me feel much better when I'm lifting heavy (in the submax range). My hypothesis is that it is because it regenerates CNS but it may be bullshit or placebo as well.
I do bloodwork every 2 months and I found that:
- higher estrogen made my HDL go up
- omega3 made my HDL go up (it should have made my LDL go down instead, but it didn't)
When it comes to gyno I have no idea, I've never researched this topic as I am 100% immune to that side effect. My prolactin and e2 used to be through the roof and I had no issues.