Very good point. The ability to tolerate continuous/high amounts of drugs is probably the most important factor on how far someone can take it.
With all the drugs that are being taken, these guys feel as though they are invincible. This androgen induced invulnerability is what leads to health problems and inevitable kidney/liver problems/failure.
No, i think it's a greatly overrated "point"
How much use people can get away with in the long run is less a difference than the great and poor response to gear can make.
If somebody gets a nice build on 500mg of anything a week plus maybe some HGH, they will not run into the same problems as a poor responder would.
You think this is impossible?
Look at Simple Simon, he uses almost trt dosages, and then look at esfitness the retard calls 6 gramms the sweet spot just because he doesnt respond to any less. And he looks like garbage.
Or Sev's "borat", 2000mg a week but less mass than an FHM magazine cover model.
Believe it or not, the biggest guys are not always the biggest users. If you think otherwise, seriously, look at esfitness. True adonis looks bigger than him.
Another factor is how long before joints, tendons and muscle nerves start going bad.