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Getbig Bodybuilding Boards => Nutrition, Products & Supplements Info => Topic started by: The True Adonis on March 24, 2007, 10:18:17 PM

Title: MORE info on The MAGIC Elixir
Post by: The True Adonis on March 24, 2007, 10:18:17 PM
http://www.newscientist.com/article/dn10590-red-wine-compound-boosts-athletic-endurance.html


Red wine compound boosts athletic endurance
17:00 16 November 2006
NewScientist.com news service

High doses of a compound found naturally in grape skins and red wine can improve muscle endurance in mice, and the compound also keeps them slim, a new study shows.

The effects of resveratrol are so pronounced that endurance athletes may one day take it as a performance enhancer, experts speculate.

Johan Auwerx at the Institute of Genetics and Molecular and Cell Biology in Illkirch, France, and colleagues placed mice on a high-fat diet. Half of those mice received daily amounts of up to 400 milligrams of resveratrol per kilogram of body weight. A person would have to drink about 100 glasses of wine in just one day to obtain a similar dose of resveratrol, Auwerx says.

After three weeks, the mice on the resveratrol supplements weighed only about 20% more than mice on a standard diet. But those on the high-fat diet that did not receive the supplement weighed 60% more than the control mice. The resveratrol also improved the rodents endurance in fitness tests, and seemed to have no toxic side effects.

Mice on the high-fat diet that also took resveratrol were able to run twice as far on a treadmill as those on the same diet but without the supplement, even after the animals’ weight differences were taken into account.

Pathway trigger
Resveratrol boosts muscle endurance by increasing the energy-producing components within muscle cells, called mitochondria, the researchers believe. Auwerx says that high-doses of resveratrol are needed to trigger the pathway that gives cells more mitochondria. “At very low doses you don’t activate the cell machinery to burn energy,” he explains, banishing the idea that the odd glass of wine might improve athletic prowess.

Mitochondria play a crucial role in burning fat to provide fuel for endurance exercise, perhaps explaining why mice on the supplement were slimmer in the study, Auwerx says.

Resveratrol might also be used to prevent muscle wasting in the elderly, says David Sinclair at Harvard Medical School in Massachusetts, US, who was not involved in this study.

Previous studies have shown the compound can extend the lifespan of mice by around 15%. And resveratrol is also being used in a clinical trial involving people with diabetes.

Journal reference: Cell (DOI: 10.1016/j.cell.2006.11.013
Title: Re: MORE info on The MAGIC Elixir
Post by: Mr. Intenseone on March 24, 2007, 10:22:53 PM
Great study................BTW, have you ever known someone who is drunk and they think they're invincible?

Think about that!
Title: Re: MORE info on The MAGIC Elixir
Post by: MikeThaMachine on March 24, 2007, 10:23:25 PM
Shut up, your retarded and we don't care.


Hope this helps...
Title: Re: MORE info on The MAGIC Elixir
Post by: Buttsuck on March 24, 2007, 10:31:41 PM
I drank red wine last night!!
Title: Re: MORE info on The MAGIC Elixir
Post by: MikeThaMachine on March 24, 2007, 10:34:46 PM
I drank red wine last night!!



I am driking a 40 of Mickey's ICE right now...
Title: Re: MORE info on The MAGIC Elixir
Post by: Mr. Intenseone on March 24, 2007, 10:36:31 PM
Shut up, your retarded and we don't care.


Hope this helps...

Who me?
Title: Re: MORE info on The MAGIC Elixir
Post by: MikeThaMachine on March 24, 2007, 10:44:02 PM
Who me?

 
Yeah ::)




Dumbass I was talking about Adonis. ;D
Title: Re: MORE info on The MAGIC Elixir
Post by: Mr. Intenseone on March 24, 2007, 10:48:02 PM

Yeah ::)




Dumbass I was talking about Adonis. ;D

hahahaha...oh...LOL, sorry!
Title: Re: MORE info on The MAGIC Elixir
Post by: youandme on March 24, 2007, 10:51:46 PM
Great study................BTW, have you ever known someone who is drunk and they think they're invincible?

Think about that!

What's you opinion on resveratrol supplementation?
Title: Re: MORE info on The MAGIC Elixir
Post by: Mr. Intenseone on March 24, 2007, 11:10:21 PM
What's you opinion on resveratrol supplementation?

As a suppliment, I really see nothing wrong with it, it's a strong antioxident that can only help, and from what I have read, it can help protect other diseases like cancer and parkinsons, but I strongly don't recommend having wine or alcohol before an endurance event..........or any event for that matter, lol!
Title: Re: MORE info on The MAGIC Elixir
Post by: pumpher on March 24, 2007, 11:15:40 PM
It's good to see more research in this area

That being said, there's a fine line between a glass a day, and an alcoholic  :P
Title: Re: MORE info on The MAGIC Elixir
Post by: chainsaw on March 25, 2007, 12:10:09 AM
http://www.newscientist.com/article/dn10590-red-wine-compound-boosts-athletic-endurance.html


Red wine compound boosts athletic endurance
17:00 16 November 2006
NewScientist.com news service

High doses of a compound found naturally in grape skins and red wine can improve muscle endurance in mice, and the compound also keeps them slim, a new study shows.

The effects of resveratrol are so pronounced that endurance athletes may one day take it as a performance enhancer, experts speculate.

Johan Auwerx at the Institute of Genetics and Molecular and Cell Biology in Illkirch, France, and colleagues placed mice on a high-fat diet. Half of those mice received daily amounts of up to 400 milligrams of resveratrol per kilogram of body weight. A person would have to drink about 100 glasses of wine in just one day to obtain a similar dose of resveratrol, Auwerx says.

After three weeks, the mice on the resveratrol supplements weighed only about 20% more than mice on a standard diet. But those on the high-fat diet that did not receive the supplement weighed 60% more than the control mice. The resveratrol also improved the rodents endurance in fitness tests, and seemed to have no toxic side effects.

Mice on the high-fat diet that also took resveratrol were able to run twice as far on a treadmill as those on the same diet but without the supplement, even after the animals’ weight differences were taken into account.

Pathway trigger
Resveratrol boosts muscle endurance by increasing the energy-producing components within muscle cells, called mitochondria, the researchers believe. Auwerx says that high-doses of resveratrol are needed to trigger the pathway that gives cells more mitochondria. “At very low doses you don’t activate the cell machinery to burn energy,” he explains, banishing the idea that the odd glass of wine might improve athletic prowess.

Mitochondria play a crucial role in burning fat to provide fuel for endurance exercise, perhaps explaining why mice on the supplement were slimmer in the study, Auwerx says.

Resveratrol might also be used to prevent muscle wasting in the elderly, says David Sinclair at Harvard Medical School in Massachusetts, US, who was not involved in this study.

Previous studies have shown the compound can extend the lifespan of mice by around 15%. And resveratrol is also being used in a clinical trial involving people with diabetes.

Journal reference: Cell (DOI: 10.1016/j.cell.2006.11.013

Go snort some cocaine while you're at it, I hear it clears the sinuses!!!!
By the way, get a life!
Title: Re: MORE info on The MAGIC Elixir
Post by: GroinkTropin on March 25, 2007, 01:41:54 AM
Great study................BTW, have you ever known someone who is drunk and they think they're invincible?

Think about that!

Yeah when i mix jager and beer that happens.
Title: Re: MORE info on The MAGIC Elixir
Post by: Rimbaud on March 25, 2007, 05:09:13 AM
I drank red wine last night!!

I had four PBR's on Friday.