"Babylon the Great" (the one mentioned in the bible) is not referring to any government. "Babylon the Great" is the world wide mix of false religion that uses the bible as it's authority in the manner which Jesus spoke of. That is, hypocritically! Jesus warned that false religion ("Babylon the Great") would be prevalent during the "last days" of this system.
So, Louis is definitely inaccurate by accusing the USA of being "Babylon the Great" if he is associating them (USA) as such.