Agreee 100%. Let me explain it this way. Many people get big off the hormones and grow quite a bit and then stop. They increase the dosage this helps a bit but then they stop again. After a while, they don't grow much anymore and they think that there receptors are shot. No, you have just reached a limit depending on your genetic makeup and other factors. You are maxed out even with the use of hormones. That is where GH and insulin come into play but that's a different topic. Now if this person were to stop working out, eating right and get off the hormones they would shrink drastically. However if they were to start working out again and start pumping the hormones, they would begin to grow again VERY quickly back up to their original size. If the receptors were shot, this would not happen.