all you latched on was "racism"....
And neglected the whole DNA manipulation to create Elephantmen---the whole effing premise. Giant walking, talking Hippos, Elephants, Crocs, Giraffes, Warthogs, with humanoid bodies, just as smart as humans, performing human jobs. They were created to be sterile---no elephantwoman created. Said beings are not permitted to have children, nor marry human women. But, what is really human? What dictates being "human".
How does one deal with sentient beings that were created to destroy humans? There are far more questions and topics than racism...it makes you think.
The graphic novels are very Blade Runner-sque.
Meh I think sci fi needs to move away from monsters and cheap action sequences.
Just so great movies don't continually get hijacked by some jewy producer with ADHD.
Gattaca from 97 is a movie that all new sci fi's should take as a reference, covers all the bases, and is exceptionally good, and did it without cgi.
I think using the same concept you mention but have it only focusing on the neurology of the gmod'd would work.
It's be interesting if different hybrids had different forums of mental disorders.
I.E. a race of people with ocd, schizo, depression, mania, etc. It's very relevant to modern day society, when every crook and criminal has a disorder, and also ties into race but in a way that isn't so simplistic, as were all the same on the inside crap you get back in the day. It can also get into the deeper philosophical issue of freedom of choice and all that jazz.