I won't touch it. If it was an opioid I would love it. Same with Kratom. Not an opioid. Does nothing to the opioid receptor at any dosage.
I lover Tram way more than the opioids I've tried. Oxy caused a very bummed out feeling in m at very low dosages, Tram is an instant antidepressant. It can also energize you, in some countries it's become a real problem among laborers.
But what would you say causes the subjective effects of both Tram and Kratom? Why do so many say Kratom can have almost miraculous effects on some who come off opiates and opioids, being almost a replacement? Not as strong as heroin or Oxy or Fent but can help some stay off those. Why did ESFitness go to heroin when he couldn't get Tram?
Do you get no effects whatsoever from Kratom? If I take enough of it has very pronounced effects, initally I thought it didn't do much but I found it definitely did at higher dosages.
The 7-mitragynine hits some of the very same receptors as Oxy and Fent. Why would the scientists lie about it? It also causes some constipation just like opiates.
https://www.scientificamerican.com/article/recreational-drug-kratom-hits-the-same-brain-receptors-as-strong-opioids/Lots of testimonials of guys saying they became very dependant on it, like on professionalmuscle. What is causing the addiction if not opioid pathways? It's also interesting how Kratom removes any withdrawals when getting off Tramadol.
One problem with Tram is the very real seizure risk, especially above like 400 milligrams. One guy I know was diagnosed as an epileptic after abusing Tram. He was getting seizures at the Police station and other public places, once docs had to put benzos in his ass to relieve the seizure. So Tram is not a drug to use very high dosages of.