what would you speculate the reason behind such a low doseage beiing effective would be ? in your opinion at what level would insulin become supraphysiological ?
I don't know is my answer to both questions.
I could search for the second question but I'm too damn lazy right now. You would have to look at peak plasma levels and total insulin released (area under curve etc) and then check how something like Humalog compares to endo insulin (since it's like an analog). Still, I'm pretty sure a normal person can release the equivalent of that as a response to a heavy glucose load. I mean, some get away with 5 grams of carbs per IU insulin (i.e 100 grams for 20IU injected) so it's not that huge of a dosage.