From Splenda.com
SPLENDAŽ No Calorie Sweetener contains sucralose (SPLENDAŽ Brand Sweetener), the no calorie sweetener made from sugar, so it tastes like sugar, with no unpleasant aftertaste. SPLENDAŽ No Calorie Sweetener can be used virtually anywhere sugar is used. It can also be used in cooking and baking in a variety of recipes. Like many no and low calorie sweeteners, each serving of SPLENDAŽ No Calorie Sweetener contains a very small amount of common food ingredients, e.g., dextrose and/or maltodextrin, for volume. Because the amount of these ingredients is so small, SPLENDAŽ No Calorie Sweetener still has an insignificant calorie value per serving and meets FDA's standards for "no calorie" sweeteners.
How was the safety of SPLENDAŽ Brand Sweetener determined?
Regulatory agencies worldwide have reviewed more than 100 safety studies on sucralose and found sucralose to be safe including the United States Food and Drug Administration, the Joint FAO/WHO Expert Committee on Food Additives (JECFA), the Health Protection Branch of Health and Welfare Canada, and Australia's National Food Authority.
Over 80 countries now permit the use of sucralose (and over 4,000 food and beverage products around the world are now sweetened with SPLENDAŽ Brand Sweetener).