you mean because of:
If glycocyamine does get past the liver intact, the effects will probably not be desirable. The fact that it competitively inhibits creatine transport is not the only reason. Glycocyamine is also transported across the blood brain barrier (BBB). This may be associated with a variety of negative effects, and the most well-known property of GAA in the brain is as a convulsant [1, 5-7]. GAA increases the production of reactive oxygen species (ROS) in the brain [1]. Other mechanisms of neurotoxicity include inhibition of Na+,K+-ATPase, decreased membrane fluidity, and interaction with the GABA-A receptor [8-9]. It is unknown whether these effects are relevant at doses used for supplementation, but it seems unlikely. They primarily become a problem in GAMT deficiency, which results in both elevated brain GAA and creatine deficiency. Still, those with a history of epilepsy should definitely stay away from glycocyamine.
i am in good health, not to worry
