Getbig Bodybuilding, Figure and Fitness Forums
Getbig Bodybuilding Boards => Steroids Info & Hardcore => Topic started by: El Diablo Blanco on January 16, 2007, 05:59:04 AM
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I have read some posts here that say you should split your oral doses such as winny during the day. From what I have read this seems like bad advice.
I believe it was Bill Lewellyn ( sorry if I mispelled you name ) said that taking one dose a day would have a single pass on you liver of a certain amount of the product. By taking two small doses you are making your liver do twice the work in one day and hence harming it. I think he said that there is a certain amount of toxicity that happens whether you take 25 or 50 mg so by splitting it you are doubling the toxicity.
I am interested to see if anyone agrees or not.
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The reason for recommending split-dosing during the day is based on the half-life of around 9 hours for oral winny. Bill's thought is an intriguing one, however I am not sure it is really founded. For example, acetaminophen (Tylenol) is extremely toxic to the liver, very much in a dose-dependent fashion. You can safely take 650mg every 6 hours for 24 hours (for a total of 2400mg in 24 hours), but a dose of 2600mg all at once would be rather hepatotoxic.
I'd have to see more evidence presented on this.
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That is not my thought. There has been no study that I know of showing that twice per day offers any more or less hepatotoxicity than one.
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That is not my thought. There has been no study that I know of showing that twice per day offers any more or less hepatotoxicity than one.
Sorry Bill, I know I read this somewhere and thought it might have been you. I will try to find the link of where I read about the toxicity being better taking it at once.
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Np.. Happens quite often. So many writers and so many thoughts out there; hard to keep track..
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Maybe it was Bill Roberts, not Bill Llewellyn who said that.
Bill Llewellyn...Bill Roberts...anthony roberts....maybe I should have stuck with hooker...our names are all too close... ;)
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The reason for recommending split-dosing during the day is based on the half-life of around 9 hours for oral winny. Bill's thought is an intriguing one, however I am not sure it is really founded. For example, acetaminophen (Tylenol) is extremely toxic to the liver, very much in a dose-dependent fashion. You can safely take 650mg every 6 hours for 24 hours (for a total of 2400mg in 24 hours), but a dose of 2600mg all at once would be rather hepatotoxic.
I'd have to see more evidence presented on this.
Egads my uncle has a bad back, and tends to take up to 20 a day. Funny thing though, hes 45, and still fairly healthy, despite a pack a day habit and shit diet. I wonder if all the cofee he drinks is keeping him alive....