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Getbig Bodybuilding Boards => Nutrition, Products & Supplements Info => Topic started by: youandme on December 03, 2007, 04:39:27 PM

Title: Anyone know of some good notropics ("smart drugs")?
Post by: youandme on December 03, 2007, 04:39:27 PM
Looking for a complete supplement that someone would like to recommend, my concetration is off, and any kind of fat burner ends up making me alert but not able to concentrate?

Thanks
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: GroinkTropin on December 03, 2007, 07:27:00 PM
I don't know if he still makes it but my buddy larry used to own a supp company that makes yohimburn, i think he made a nootropic can't remember the nam of it. I'll look for it.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: GroinkTropin on December 03, 2007, 07:28:48 PM
Ah here it is, good to see his company still running strong.

https://www.anafit.com/shop/product_info.php?cartID=c66e5086ab8378793844fca235e4caee&id=66
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Princess L on December 03, 2007, 08:29:17 PM
Looking for a complete supplement that someone would like to recommend, my concetration is off, and any kind of fat burner ends up making me alert but not able to concentrate?

Thanks

The DHA component in fish oil would be good for that.  You can get DHA separately too.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: GroinkTropin on December 04, 2007, 12:58:29 AM
The DHA component in fish oil would be good for that.  You can get DHA separately too.

Is it stil effective taken on its own? And why would you recommend it be taken seperately?
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: DK II on December 04, 2007, 01:19:46 AM
Zen Meditation, every morning 15 minutes on an empty stomach.

Costs nothing and helps to refresh and learn to concentrate.

Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: GroinkTropin on December 04, 2007, 05:32:59 AM
Zen Meditation, every morning 15 minutes on an empty stomach.

Costs nothing and helps to refresh and learn to concentrate.



It also does nothing but thanks for the tip.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: DK II on December 04, 2007, 05:39:58 AM
It also does nothing but thanks for the tip.

That's not quite right, but here's not the place to discuss that.

It helps as much as those pills for concentration, if not better and has no side.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: wood on December 04, 2007, 06:57:18 AM
Vinpocetine?
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Princess L on December 04, 2007, 07:21:32 AM
Is it stil effective taken on its own? And why would you recommend it be taken seperately?

Good question  ;)  Not totally sure as I haven't researched that specifically, however, it is well known that the EPA component in fish oil is good for overall maintenance and heart health and the DHA component is good for brain function stuff.  They put DHA in baby formula for brain development and DHA has been shown to be helpful with other brain 'issues' such as ADD/ADHD, dementia, Alzheimer's, depression, Schizophrenia, and other cognitive impairments...
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: youandme on December 04, 2007, 07:56:49 AM
Zen Meditation, every morning 15 minutes on an empty stomach.

Costs nothing and helps to refresh and learn to concentrate.




Thanks I'll look into this.

DHA yeah I've heard it help with myelin sheath development, and oribital sensory nerves, but then I remember reading up on some dosage issues.

Thanks guys
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: 1Fast400 on December 04, 2007, 09:02:14 AM
http://www.mindandmuscle.net/forum/index.php?showforum=41

Tons of reading on that board.  Nootropics is a very large and diverse topic
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: youandme on December 04, 2007, 10:40:15 AM
http://www.mindandmuscle.net/forum/index.php?showforum=41

Tons of reading on that board.  Nootropics is a very large and diverse topic

Thanks bro, great find.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 13, 2007, 02:14:02 AM
Looking for a complete supplement that someone would like to recommend, my concetration is off, and any kind of fat burner ends up making me alert but not able to concentrate?

Thanks

  There are basically two types of smart drugs, cholinergic agents and ergoloid mesylate alkaloids. The first kind include drugs such as piracetam, a GABA-derived compound that inhibits dopamine release thus causing it's accumulation in the pre-synaptic cleft. This class of drugs works primarilly by loading neurons with neurotransmitters that get depleted due to stress - and by stimulatory substances sych as caffeine and nicotine. They make you smarter by making your thinking quicker and giving you mental energy.

  Ergoloid mesylates are alkaloids from rye. They work differently from cholinergic agents: while cholinergic agents make you smarter by increasing synaptic levels of dopamine by inhibiting it's release, rye alkoloids work by increasing blood and oxygen flow to the brain as well as stimulating the formation of new dendrites. Cholinergic agents only allow you to use your intelligence to the best of it's capacity by giving you more mental energy, but rye alkaloids might actually increase intelligence itself by boosting dendrital density. It is speculative, but probable. I believe that mesylate ergoloids are more efrfective smart drugs than cholinergic agents due to their dendrite-boosting effect. However, cholinergic agents should be used for a few weeks while abstaining from caffeine to load depleted dopamine levels. After your pre-synaptic cleft is loaded with dopamine, cholinergic compounds become irrelevant, and you should use only ergoloid mesylates to stimulate the formation of new dendrites. A dose of 9 mg a day is effective for most adult men.

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: The Master on December 13, 2007, 05:07:31 AM
  There are basically two types of smart drugs, cholinergic agents and ergoloid mesylate alkaloids. The first kind include drugs such as piracetam, a GABA-derived compound that inhibits dopamine release thus causing it's accumulation in the pre-synaptic cleft. This class of drugs works primarilly by loading neurons with neurotrasmitters that get depleted due to stress - and by stimulatory substances sych as caffeine and nicotine. They make you smarter by making your thinking quicker and giving you mental energy.

  Ergoloid mesylates are alkaloids from rye. They work differently from cholinergic agents: while cholinergic agents make you smarter by increasing synaptic levels of dopamine by inhibiting it's release, rye alkoloids work by increasing blood and oxygen flow to the brain as well as stimulating the formation of new dendrites. Cholinergic agents only allow you to use your intelligence to the best of it's capacity by giving you more mental energy, but rye alkaloids might actually increase intelligence itself by boosting dendrital density. It is speculative, but probable. I believe that mesylate ergoloids are more efrfective smart drugs than cholinergic agents due to their dendrite-boosting effect. However, cholinergic agents should be used for a few weeks while abstaining from caffeine to load depleted dopamine levels. After your pre-synaptic cleft is loaded with dopamine, cholinergic compounds become irrelevant, and you should use only ergoloid mesylates to stimulate the formation of new dendrites. A dose of 9 mg a day is effective for most adult men.

SUCKMYMUSCLE

Have you tried these substances yourself?
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: smaul on December 13, 2007, 06:38:45 AM
That's not quite right, but here's not the place to discuss that.

It helps as much as those pills for concentration, if not better and has no side.

Why do it the hard way when you can do it the easy way with drugs?
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 14, 2007, 03:47:29 PM
Have you tried these substances yourself?

  Yes. Why? Does it show? ;)

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: The Master on December 14, 2007, 04:38:28 PM
  Yes. Why? Does it show? ;)

SUCKMYMUSCLE

What are your experiences with them? The Ergoloid mesylates sounds interesting, if you tried "them", did you get any nasty side effects? How did they affect your cognitive abilities?

In all fairness, you do write some very good posts.  :)
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 14, 2007, 07:29:00 PM
there are a few nootropics that i routinely use.

for beginners any of the cetam's would be a good choice, with piracetam, aniracetam, oxiaracetam being the most popular wiht piracetam being the mildest. some normal nootrophics people might know of a vasodialators like ginko biloba and a good standby called bacopa monerii which is both a carminitive as well as mast cells stabilizer. you would have to add a choline donor such as alpha gpc or choline bitarate to avoid fuzziness. most of cetams have anxiolytic effects as well.

subletamine is another highly effective nootropic which is higly effect, there are others like  Huperzine A 
Galantamine,Idebenone,DMAE,  Acetyl L-Carnitine,Pyritinol,Centrophenoxine etc..  but youd have to do your research if you where to use some of these compounds as you could build quite a stack if you had some knowledge.

another novel nootropic i have used is picamilon which is basically gaba bound to niacin which allows for access to the brain, because gaba does not cross the BBB via oral administration. it is mainly used as an anxiolytic, anti depressant, but has a unique stimulating, and relaxing effect at high doses, its also cheap!!

my adivice is to stick with a cetam, most likely piracetam as its mild and most studied. all nootrophics are inherently toxic, and may potentiate glutamate degeneration as seen in alzheimers. the info is clouded with some studies showing neuroprotection while others showing possible toxicity not related to drug levels. thus try piracetam at low-moderate doses, and you may potentiate it with a vasodialator like picamilon or gingko if you need a little more kick. good old caffiene is a nice nootrophic as well which shows increase in global concentration. thats a bit of info but its a run down of some, as there are many with many many mechanisms of action.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 14, 2007, 07:33:53 PM
  There are basically two types of smart drugs, cholinergic agents and ergoloid mesylate alkaloids. The first kind include drugs such as piracetam, a GABA-derived compound that inhibits dopamine release thus causing it's accumulation in the pre-synaptic cleft. This class of drugs works primarilly by loading neurons with neurotransmitters that get depleted due to stress - and by stimulatory substances sych as caffeine and nicotine. They make you smarter by making your thinking quicker and giving you mental energy.

  Ergoloid mesylates are alkaloids from rye. They work differently from cholinergic agents: while cholinergic agents make you smarter by increasing synaptic levels of dopamine by inhibiting it's release, rye alkoloids work by increasing blood and oxygen flow to the brain as well as stimulating the formation of new dendrites. Cholinergic agents only allow you to use your intelligence to the best of it's capacity by giving you more mental energy, but rye alkaloids might actually increase intelligence itself by boosting dendrital density. It is speculative, but probable. I believe that mesylate ergoloids are more efrfective smart drugs than cholinergic agents due to their dendrite-boosting effect. However, cholinergic agents should be used for a few weeks while abstaining from caffeine to load depleted dopamine levels. After your pre-synaptic cleft is loaded with dopamine, cholinergic compounds become irrelevant, and you should use only ergoloid mesylates to stimulate the formation of new dendrites. A dose of 9 mg a day is effective for most adult men.

SUCKMYMUSCLE

 just to add to this point ssris have shown to aid neuronal growth as well as ashwagandha which is pretty interesting. wellbutrin is a prescription drug worth looking in too for motivation and concentration, but in some it causes fog which is interesting.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 14, 2007, 07:42:28 PM
http://smart-nutrition.net/JamesSouth-piracetam.htm



great article on piracetam and best website to buy from
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: The Master on December 14, 2007, 08:04:30 PM
there are a few nootropics that i routinely use.

for beginners any of the cetam's would be a good choice, with piracetam, aniracetam, oxiaracetam being the most popular wiht piracetam being the mildest. some normal nootrophics people might know of a vasodialators like ginko biloba and a good standby called bacopa monerii which is both a carminitive as well as mast cells stabilizer. you would have to add a choline donor such as alpha gpc or choline bitarate to avoid fuzziness. most of cetams have anxiolytic effects as well.

subletamine is another highly effective nootropic which is higly effect, there are others like  Huperzine A 
Galantamine,Idebenone,DMAE,  Acetyl L-Carnitine,Pyritinol,Centrophenoxine etc..  but youd have to do your research if you where to use some of these compounds as you could build quite a stack if you had some knowledge.

another novel nootropic i have used is picamilon which is basically gaba bound to niacin which allows for access to the brain, because gaba does not cross the BBB via oral administration. it is mainly used as an anxiolytic, anti depressant, but has a unique stimulating, and relaxing effect at high doses, its also cheap!!

my adivice is to stick with a cetam, most likely piracetam as its mild and most studied. all nootrophics are inherently toxic, and may potentiate glutamate degeneration as seen in alzheimers. the info is clouded with some studies showing neuroprotection while others showing possible toxicity not related to drug levels. thus try piracetam at low-moderate doses, and you may potentiate it with a vasodialator like picamilon or gingko if you need a little more kick. good old caffiene is a nice nootrophic as well which shows increase in global concentration. thats a bit of info but its a run down of some, as there are many with many many mechanisms of action.



Great post!
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: BFP on December 14, 2007, 09:04:08 PM
Looking for a complete supplement that someone would like to recommend, my concetration is off, and any kind of fat burner ends up making me alert but not able to concentrate?

Thanks
[/quote

Im a huge fan of
Deprynyl
Piracetam
Aniracitam
Oxiracetam
Clear Edge
and Huperzine-A.  Just watch with any of the racetams, and especially piracetam.  It depletes choline and gives a mean fucking headache while doing it.  A little Aplha GPC or Lecithin will handle it though.  Piracetam also has a wierd dose response curve.

Jason
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 14, 2007, 09:35:08 PM
Looking for a complete supplement that someone would like to recommend, my concetration is off, and any kind of fat burner ends up making me alert but not able to concentrate?

Thanks
[/quote

Im a huge fan of
Deprynyl
Piracetam
Aniracitam
Oxiracetam
Clear Edge
and Huperzine-A.  Just watch with any of the racetams, and especially piracetam.  It depletes choline and gives a mean fucking headache while doing it.  A little Aplha GPC or Lecithin will handle it though.  Piracetam also has a wierd dose response curve.

Jason

bump for deprenyl i love it as a drug, may cause agitation and anxiety in those prone to it however it should increase sexual desire and mood quite effectively.  what dosage do you use and what effects do you receive, with regards to mood, concentration etc. i apologize if anyone read my unedited version, i stated it had a tyramine effect but realized its a MAOI-B so it does not have this side.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Princess L on December 14, 2007, 09:41:39 PM
there are a few nootropics that i routinely use.

for beginners any of the cetam's would be a good choice, with piracetam, aniracetam, oxiaracetam being the most popular wiht piracetam being the mildest. some normal nootrophics people might know of a vasodialators like ginko biloba and a good standby called bacopa monerii which is both a carminitive as well as mast cells stabilizer. you would have to add a choline donor such as alpha gpc or choline bitarate to avoid fuzziness. most of cetams have anxiolytic effects as well.

subletamine is another highly effective nootropic which is higly effect, there are others like  Huperzine A 
Galantamine,Idebenone,DMAE,  Acetyl L-Carnitine,Pyritinol,Centrophenoxine etc..  but youd have to do your research if you where to use some of these compounds as you could build quite a stack if you had some knowledge.

another novel nootropic i have used is picamilon which is basically gaba bound to niacin which allows for access to the brain, because gaba does not cross the BBB via oral administration. it is mainly used as an anxiolytic, anti depressant, but has a unique stimulating, and relaxing effect at high doses, its also cheap!!

my adivice is to stick with a cetam, most likely piracetam as its mild and most studied. all nootrophics are inherently toxic, and may potentiate glutamate degeneration as seen in alzheimers. the info is clouded with some studies showing neuroprotection while others showing possible toxicity not related to drug levels. thus try piracetam at low-moderate doses, and you may potentiate it with a vasodialator like picamilon or gingko if you need a little more kick. good old caffiene is a nice nootrophic as well which shows increase in global concentration. thats a bit of info but its a run down of some, as there are many with many many mechanisms of action.

  You're speaking Greek  :-[
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 14, 2007, 09:50:15 PM
  You're speaking Greek  :-[
[/quote


sorry for the medical jargon, i just find the words more correct but i will clarify if some people are interested in anything in the post they might not understand.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 14, 2007, 10:58:01 PM
  You're speaking Greek  :-[

  Really? The pharmacological and biochemical lexicon used there is actually very basic. Anyone with no more than 2 years of college organic chemistry would have no problem understanding it. If you find this complicated, I have no idea what you would find simple.

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 14, 2007, 11:01:28 PM
  I must point that monoamine-oxidase B inhibitors, like selegiline, might turn out to be far more effective on a miligram to miligram basis to load the pre-synaptic cleft with dopamine than GABA-derived dopamine antagonists like piracetam. The problem is that selegiline is much harder to get by than piracetam - and also it is a controlled substance.

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Archer77 on December 15, 2007, 04:38:12 PM
  I must point that monoamine-oxidase B inhibitors, like selegiline, might turn out to be far more effective on a miligram to miligram basis to load the pre-synaptic cleft with dopamine than GABA-derived dopamine antagonists like piracetam. The problem is that selegiline is much harder to get by than piracetam - and also it is a controlled substance.

SUCKMYMUSCLE

you can import a three month supply from abroad and its completely lega.  Ive done it a few times.  Its just a bit more expensive
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 15, 2007, 05:24:33 PM
you can import a three month supply from abroad and its completely lega.  Ive done it a few times.  Its just a bit more expensive


its a very potent dopamine agonist, lower doses seem to work much better. how do you find it? any anti depressant effect? does it increase anxiety and agitation.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: trab on December 15, 2007, 05:28:58 PM
  I must point that monoamine-oxidase B inhibitors, like selegiline, might turn out to be far more effective on a miligram to miligram basis to load the pre-synaptic cleft with dopamine than GABA-derived dopamine antagonists like piracetam. The problem is that selegiline is much harder to get by than piracetam - and also it is a controlled substance.

SUCKMYMUSCLE

And your afraid of steroids?  ::)
I bet Your #1 intake is warm liquid protine... Both oral and rectal.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 15, 2007, 07:07:59 PM
And your afraid of steroids?  ::)
I bet Your #1 intake is warm liquid protine... Both oral and rectal.

deprenyl has shown to extend life in rats up to 20% and may offer some of the same life extending properties in humans, i would say it would add a couple of quality years to your life. its an life extenstion drug. it has little sides, and numerous quality of life producing benefits. steriods tend to shorten the life span, and can result in lower quality of life in the long haul, deprenyl is the opposite.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: BFP on December 15, 2007, 07:13:02 PM
  I must point that monoamine-oxidase B inhibitors, like selegiline, might turn out to be far more effective on a miligram to miligram basis to load the pre-synaptic cleft with dopamine than GABA-derived dopamine antagonists like piracetam. The problem is that selegiline is much harder to get by than piracetam - and also it is a controlled substance.

SUCKMYMUSCLE

Ive found that selegiline should be taken with stims for the best effect.  Like I said before, Im not a fan of the piracetam (my least favorite racetam) due to the wierd dosage curve.  If you are worried about the legalities, I think you would find oxiracetam to be a much better option.

Jason
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: trab on December 15, 2007, 07:45:07 PM
deprenyl has shown to extend life in rats up to 20% and may offer some of the same life extending properties in humans, i would say it would add a couple of quality years to your life. its an life extenstion drug. it has little sides, and numerous quality of life producing benefits. steriods tend to shorten the life span, and can result in lower quality of life in the long haul, deprenyl is the opposite.

"May"   ::)
You dont know tomorow kiddie.
Ive allready outlived a antisteroid Dr I had, and he was younger than I... ;)
Enjoy....
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 15, 2007, 07:50:43 PM
And your afraid of steroids?  ::)
I bet Your #1 intake is warm liquid protine... Both oral and rectal.

  Every drug has an array of effects, both positive and negative you moron. I never recommended selegiline for health, but for loading the pre-synaptic cleft of neuronal axons by inhibiting monoamine-oxidase B. Just like steroids, it has it's pros and cons. Having said that, I believe that the cons of androgens, especially 17-alpha-alkylated ones, is much greater than selegiline. Now STFU because the adults are having a conversation. ;)

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 15, 2007, 07:58:42 PM
"May"   ::)
You dont know tomorow kiddie.
Ive allready outlived a antisteroid Dr I had, and he was younger than I... ;)
Enjoy....

sorry i geuss your not aware that science doesnt have all the answers. its a very popular drug among life extension proponents and doctors in europe. as an anti depressant it has few sides and many benefits, like increased libido which is often surpressed in some depressants like ssris etc..

i never said steriods where bad, but are definitly way more dangerous then deprenyl for the most part. i like steriods for hrt and when im older i wouldnt be adverse to taking them at low dosage to maintain some of the benefits. taking drugs at the level bodybuilders do is abuse, they are drug addicts. appropriate dosages done right can be very beneficial in the long term.

just because you outlived your doctor doesnt mean shit, its funny that you point out MAY like i dont have proof, but you use a retarded example like you outliving your doctor as proof that steriods arent bad. i suppose if i get hit  by a car tommorrow and you outlive me, then steriods are safe. all drugs have problems and benefits, but national level, and pros are drugs abusing addicts(without the physical dependency), you cant disagree with that.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: trab on December 15, 2007, 07:59:12 PM
  Every drug has an array of effects, both positive and negative you moron. I never recommended selegiline for health, but for loading the pre-synaptic cleft of neuronal axons by inhibiting monoamine-oxidase B. Just like steroids, it has it's pros and cons. Having said that, I believe that the cons of androgens, especially 17-alpha-alkylated ones, is much greater than selegiline. Now STFU because the adults are having a conversation. ;)

SUCKMYMUSCLE

Adult, you little piss ant bitch... Your punk ass was still shittin itself while I was humpin fassion modle material chicks...
And I still am...  ;D
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: trab on December 15, 2007, 08:02:55 PM
sorry i geuss your not aware that science doesnt have all the answers. its a very popular drug among life extension proponents and doctors in europe. as an anti depressant it has few sides and many benefits, like increased libido which is often surpressed in some depressants like ssris etc..

i never said steriods where bad, but are definitly way more dangerous then deprenyl for the most part. i like steriods for hrt and when im older i wouldnt be adverse to taking them at low dosage to maintain some of the benefits. taking drugs at the level bodybuilders do is abuse, they are drug addicts. appropriate dosages done right can be very beneficial in the long term.

just because you outlived your doctor doesnt mean shit, its funny that you point out MAY like i dont have proof, but you use a retarded example like you outliving your doctor as proof that steriods arent bad. i suppose if i get hit  by a car tommorrow and you outlive me, then steriods are safe. all drugs have problems and benefits, but national level, and pros are drugs abusing addicts(without the physical dependency), you cant disagree with that.

Many are abusing, but youd be surprised how many dont abuse. They are just big to start.
"All drugs" is the excuse of the ppl who dont gain.  Some these big boys are on womens cycles.
Shit, there giant dudes taht are natural, juice them up and ya'd have a 500lb guy.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: The Master on December 15, 2007, 08:11:31 PM
Many are abusing, but youd be surprised how many dont abuse. They are just big to start.
"All drugs" is the excuse of the ppl who dont gain.  Some these big boys are on womens cycles.
Shit, there giant dudes taht are natural, juice them up and ya'd have a 500lb guy.



IDIOST
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: suckmymuscle on December 15, 2007, 08:26:20 PM

IDIOST

  He is definitely a moron. You can see by his grammatical and ortographic mistakes, as well as his poor ability to infer and deduce logically, that he is not intelligent. I do not even argue with him any more because frankly it's not worth it.

SUCKMYMUSCLE
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Alex23 on December 15, 2007, 08:28:02 PM
there are a few nootropics that i routinely use.

for beginners any of the cetam's would be a good choice, with piracetam, aniracetam, oxiaracetam being the most popular wiht piracetam being the mildest. some normal nootrophics people might know of a vasodialators like ginko biloba and a good standby called bacopa monerii which is both a carminitive as well as mast cells stabilizer. you would have to add a choline donor such as alpha gpc or choline bitarate to avoid fuzziness. most of cetams have anxiolytic effects as well.

subletamine is another highly effective nootropic which is higly effect, there are others like  Huperzine A 
Galantamine,Idebenone,DMAE,  Acetyl L-Carnitine,Pyritinol,Centrophenoxine etc..  but youd have to do your research if you where to use some of these compounds as you could build quite a stack if you had some knowledge.

another novel nootropic i have used is picamilon which is basically gaba bound to niacin which allows for access to the brain, because gaba does not cross the BBB via oral administration. it is mainly used as an anxiolytic, anti depressant, but has a unique stimulating, and relaxing effect at high doses, its also cheap!!

my adivice is to stick with a cetam, most likely piracetam as its mild and most studied. all nootrophics are inherently toxic, and may potentiate glutamate degeneration as seen in alzheimers. the info is clouded with some studies showing neuroprotection while others showing possible toxicity not related to drug levels. thus try piracetam at low-moderate doses, and you may potentiate it with a vasodialator like picamilon or gingko if you need a little more kick. good old caffiene is a nice nootrophic as well which shows increase in global concentration. thats a bit of info but its a run down of some, as there are many with many many mechanisms of action.


Any pharmaceutical names?


[tag: search]
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: BFP on December 15, 2007, 08:34:16 PM
Any pharmaceutical names?


[tag: search]

Everything in that post, save for the seligiline and sulbutamine can be had over the counter.

Jason
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Alex23 on December 15, 2007, 08:37:30 PM
Everything in that post, save for the seligiline and sulbutamine can be had over the counter.

Jason

Oh I'll look for it then... I'm witty by nature so imagine what a dopamine release inhibitor could do.
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 15, 2007, 08:39:00 PM
Everything in that post, save for the seligiline and sulbutamine can be had over the counter.

Jason

sulbutamine can be bought at bulk nutrition, i didnt think it was controlled.


smartnutrition is a great
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: BFP on December 15, 2007, 09:08:32 PM
sulbutamine can be bought at bulk nutrition, i didnt think it was controlled.


smartnutrition is a great

o'rly?  Perhaps Im confused.  I thought it was controlled.  Im an idiot sometimes I guess ;D

uniquenutrition.net can get everything mentioned in this thread.  Everything.

Jason
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: Necrosis on December 15, 2007, 09:14:59 PM
o'rly?  Perhaps Im confused.  I thought it was controlled.  Im an idiot sometimes I guess ;D

uniquenutrition.net can get everything mentioned in this thread.  Everything.

Jason

 unique nutrition is awesome also, lots of good euro drugs there too like tianeptine
Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: youandme on January 05, 2008, 10:03:34 AM
Oh I'll look for it then... I'm witty by nature so imagine what a dopamine release inhibitor could do.

Alex did you get any yet? Let us know if you have tried it.


Title: Re: Anyone know of some good notropics ("smart drugs")?
Post by: macro on March 14, 2008, 10:43:01 AM
selegiline and neurogenex are quite effective.

cardiovascular training

Hydration (mental and physical performance suffer without it)