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Getbig Main Boards => Politics and Political Issues Board => Topic started by: 240 is Back on February 11, 2009, 07:45:57 PM

Title: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 11, 2009, 07:45:57 PM

Are you for, or against, stem-cell research?

Would you object to stem-sell research if it could eradicate HIV in the world within five years?



A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.


The patient underwent a stem cell transplant and since, has not tested positive for HIV in his blood.

 "The patient is fine," said Dr. Gero Hutter of Charite Universitatsmedizin Berlin in Germany. "Today, two years after his transplantation, he is still without any signs of HIV disease and without antiretroviral medication."

The case was first reported in November, and the new report is the first official publication of the case in a medical journal. Hutter and a team of medical professionals performed the stem cell transplant on the patient, an American living in Germany, to treat the man's leukemia, not the HIV itself.

http://www.cnn.com/2009/HEALTH/02/11/health.hiv.stemcell/
Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 11, 2009, 07:48:04 PM
If you oppose it, look at this picture.  Remember there are 30 miillion people in Africa with HIV - many of them children.

Now answer the question.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: tu_holmes on February 11, 2009, 07:51:57 PM
I've always been for it... but this is just fantastic news

Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 11, 2009, 07:54:42 PM
I've always been for it... but this is just fantastic news

Same here.  The surgery is a risky one, and not yet cost-feasible. 

But once you have dollar signs and 'save the world' thoughts in the minds of millions of researchers and doctors worldwide, it'll just be a matter of time until these logistical problems are overcome.

We really may see a cure for HIV in our lifetime.  Unbelievable.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: BayGBM on February 11, 2009, 08:09:18 PM
This is truly stunning news!  I wrote about the CCR5 delta32 mutation and its implication for HIV treatments/vaccines here back in 2007.
http://www.getbig.com/boards/index.php?topic=133463.msg1889091#msg1889091

I do not yet think this is cause to get excited; I remain cautiously optimistic.

I have always been a proponent of stem cell research--even the kind that destroys embryos that are a couple weeks old.

Title: Re: Man appears free of HIV after stem cell transplant
Post by: Hugo Chavez on February 11, 2009, 08:12:01 PM
I thought they didn't even have to mess with embryos now to do stem cell stuff?   Why would anyone have a reason to be against it now?  I mean besides for those who want to see the world depopulated as much as possible.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 11, 2009, 08:16:41 PM
1. People are meant to die

2.  If a country wants to fund it on their own, that's fine but WE don't have 30 million dying of AIDS.  Let those countries deal with it themselves.  We have enough problems to deal with here without trying to solve everyone elses problems.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: BayGBM on February 11, 2009, 08:20:00 PM
I thought they didn't even have to mess with embryos now to do stem cell stuff?   Why would anyone have a reason to be against it now?  I mean besides for those who want to see the world depopulated as much as possible.

Wrong.  There are different kinds of stem cells.  Embryonic stem cells (the ones culled form newly formed embryos) are the most versatile, potent, and useful in research.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Hugo Chavez on February 11, 2009, 08:20:08 PM
1. People are meant to die

2.  If a country wants to fund it on their own, that's fine but WE don't have 30 million dying of AIDS.  Let those countries deal with it themselves.  We have enough problems to deal with here without trying to solve everyone elses problems.
dude, think of all the new debauchery we'd see in porn with all those worries gone.  what the hell is wrong with you man :D
Title: Re: Man appears free of HIV after stem cell transplant
Post by: BayGBM on February 11, 2009, 08:21:12 PM
1. People are meant to die

2.  If a country wants to fund it on their own, that's fine but WE don't have 30 million dying of AIDS.  Let those countries deal with it themselves.  We have enough problems to deal with here without trying to solve everyone elses problems.

Shall we all take a guess at how many degrees this poster has? ::)
Title: Re: Man appears free of HIV after stem cell transplant
Post by: MB_722 on February 11, 2009, 08:23:56 PM
mean besides for those who want to see the world depopulated as much as possible.

as I was reading 240s post, had the same thought  8)
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Hugo Chavez on February 11, 2009, 08:26:56 PM
Wrong.  There are different kinds of stem cells.  Embryonic stem cells (the ones culled form newly formed embryos) are the most versatile, potent, and useful in research.
looks like they're advancing pretty fast toward it tho.


January 2007 - Scientists at Wake Forest University led by Dr. Anthony Atala and Harvard University report discovery of a new type of stem cell in amniotic fluid.[39] This may potentially provide an alternative to embryonic stem cells for use in research and therapy.[40]

June 2007 - Research reported by three different groups shows that normal skin cells can be reprogrammed to an embryonic state in mice.[41] In the same month, scientist Shoukhrat Mitalipov reports the first successful creation of a primate stem cell line through somatic cell nuclear transfer[42]

October 2007 - Mario Capecchi, Martin Evans, and Oliver Smithies win the 2007 Nobel Prize for Physiology or Medicine for their work on embryonic stem cells from mice using gene targeting strategies producing genetically engineered mice (known as knockout mice) for gene research.[43]

November 2007 - Human Induced pluripotent stem cells: Two similar papers released by their respective journals prior to formal publication: in Cell by Kazutoshi Takahashi and Shinya Yamanaka, "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors",[44] and in Science by Junying Yu, et al., from the research group of James Thomson, "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells":[45] pluripotent stem cells generated from mature human fibroblasts. It is possible now to produce a stem cell from almost any other human cell instead of using embryos as needed previously, albeit the risk of tumorigenesis due to c-myc and retroviral gene transfer remains to be determined.

January 2008 - Robert Lanza and colleagues at Advanced Cell Technology and UCSF create the first human embryonic stem cells without destruction of the embryo[46]

January 2008 - Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts[47]
February 2008 - Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach: these iPS cells seem to be more similar to embryonic stem cells than the previous developed iPS cells and not tumorigenic, moreover genes that are required for iPS cells do not need to be inserted into specific sites, which encourages the development of non-viral reprogramming techniques. [48][49]

March 2008-The first published study of successful cartilage regeneration in the human knee using autologous adult mesenchymal stem cells is published by Clinicians from Regenerative Sciences[50]

October 2008 - Sabine Conrad and colleagues at Tübingen, Germany generate pluripotent stem cells from spermatogonial cells of adult human testis by culturing the cells in vitro under leukemia inhibitory factor (LIF) supplementation. [51]

October 2008 - Embryonic-like stem cells from a single human hair.[52]

http://en.wikipedia.org/wiki/Stem_cell#Key_research_events
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Hugo Chavez on February 11, 2009, 08:27:40 PM
Shall we all take a guess at how many degrees this poster has? ::)
33 ;D
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 11, 2009, 08:30:56 PM
dude, think of all the new debauchery we'd see in porn with all those worries gone.  what the hell is wrong with you man :D
Haha...MORE SASHA GREY!  And it's only 31 degrees....geez.   ::) ;D

Seriously, I guarantee the people backing this are expecting the US to dump billions into Africa to solve their problems but I think that would be stupid.  Wouldn't it be better to isolate it and start over, at least in Africa?

Shall we all take a guess at how many degrees this poster has? ::)
Gee, I guess we can all wonder why you would be okay with this huh Bay?
Title: Re: Man appears free of HIV after stem cell transplant
Post by: BayGBM on February 11, 2009, 08:43:51 PM
Haha...MORE SASHA GREY!  And it's only 31 degrees....geez.   ::) ;D

Seriously, I guarantee the people backing this are expecting the US to dump billions into Africa to solve their problems but I think that would be stupid.  Wouldn't it be better to isolate it and start over, at least in Africa?
 Gee, I guess we can all wonder why you would be okay with this huh Bay?

The good news (for both of us) is getbig is probably the only place where someone like you will ever have cause to interact with someone like me.  I truly hope you find the measure of happiness in life that your level of thinking allows.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 11, 2009, 08:50:23 PM
The good news (for both of us) is getbig is probably the only place where someone like you will ever have cause to interact with someone like me.  I truly hope you find the measure of happiness in life that your level of thinking allows.
Nope, I have plenty of people who share my opinions.  I'm happy thinking my way because 1.) it works for me, 2.) I believe it, 3.) curing all the world's problems is not the purpose of the US.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Hugo Chavez on February 11, 2009, 08:55:51 PM
Nope, I have plenty of people who share my opinions.  I'm happy thinking my way because 1.) it works for me, 2.) I believe it, 3.) curing all the world's problems is not the purpose of the US.
well, it's not just about AIDs either.  So many could be saved or have their pain releaved and live a normal life.  It's not about living forever and someday it might be about saving someone you love.  240 just used africa as an example.  There are countless uses.  The same agrument you make could have been made for most past medical advances.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 11, 2009, 09:01:01 PM
well, it's not just about AIDs either.  So many could be saved or have their pain releaved and live a normal life.  It's not about living forever and someday it might be about saving someone you love.  240 just used africa as an example.  There are countless uses.  The same agrument you make could have been made for most past medical advances.
True, but in this case it's AIDS.  My opinion may mean little to people making policy but I think stem cells are a mixed blessing.  Everyone is entitled their own opinion but with regards to AIDS I think we'd end up doing WAY more than just helping people in this country.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: tu_holmes on February 11, 2009, 09:04:24 PM
True, but in this case it's AIDS.  My opinion may mean little to people making policy but I think stem cells are a mixed blessing.  Everyone is entitled their own opinion but with regards to AIDS I think we'd end up doing WAY more than just helping people in this country.

Glad they didn't think of Polio like you think of AIDS.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 11, 2009, 09:06:53 PM
curing all the world's problems is not the purpose of the US.

one million americans are HIV+.

You don't think saving a million american lives is a good thing?
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Dan-O on February 11, 2009, 10:20:19 PM
Glad they didn't think of Polio like you think of AIDS.

::)  Oh brother...

Gee, was polio ever a sexually transmitted disease?  What a lame comparison.  The only innocent victims of AIDS are the kids who are born with it through no fault of their own because of their parents' carelessness and/or ignorance.  And those who have been transfused with tainted blood.  Remember the dentist who deliberately infected his patients just to "prove" that AIDS wasn't "just a gay disease?"

If there was as much hoopla about heart disease or cancer (which affect a FAR greater number of people than AIDS) as there is about AIDS, they'd probably have been cured by now.  AIDS AIDS AIDS, blah blah blah.  That being said...  hey, if there's a potential cure found, then that's great.

Listen, I know AIDS is a dreadful, horrible disease that I wouldn't wish on anyone.  It just kinda rankles me to see it getting sooo much attention when it's far from the worst health issue facing people in the US especially.  There are so many other critical issues where we could be getting more bang for our buck.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: tu_holmes on February 11, 2009, 10:28:39 PM
::)  Oh brother...

Gee, was polio ever a sexually transmitted disease?  What a lame comparison.  The only innocent victims of AIDS are the kids who are born with it through no fault of their own because of their parents' carelessness and/or ignorance.  And those who have been transfused with tainted blood.  Remember the dentist who deliberately infected his patients just to "prove" that AIDS wasn't "just a gay disease?"

If there was as much hoopla about heart disease or cancer (which affect a FAR greater number of people than AIDS) as there is about AIDS, they'd probably have been cured by now.  AIDS AIDS AIDS, blah blah blah.  That being said...  hey, if there's a potential cure found, then that's great.

Listen, I know AIDS is a dreadful, horrible disease that I wouldn't wish on anyone.  It just kinda rankles me to see it getting sooo much attention when it's far from the worst health issue facing people in the US especially.  There are so many other critical issues where we could be getting more bang for our buck.

But it is a problem to HUMANS around the world... This isn't about the US.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Eyeball Chambers on February 12, 2009, 01:04:31 AM
curing all the world's problems is not the purpose of the US.

I thought you supported Operation Iraqi Freedom?  ???
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Fury on February 12, 2009, 05:23:33 AM

Are you for, or against, stem-cell research?

Would you object to stem-sell research if it could eradicate HIV in the world within five years?



A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.


The patient underwent a stem cell transplant and since, has not tested positive for HIV in his blood.

 "The patient is fine," said Dr. Gero Hutter of Charite Universitatsmedizin Berlin in Germany. "Today, two years after his transplantation, he is still without any signs of HIV disease and without antiretroviral medication."

The case was first reported in November, and the new report is the first official publication of the case in a medical journal. Hutter and a team of medical professionals performed the stem cell transplant on the patient, an American living in Germany, to treat the man's leukemia, not the HIV itself.

http://www.cnn.com/2009/HEALTH/02/11/health.hiv.stemcell/

Of course I'm for it. Religion should not get in the way of scientific progress. The potential advances in medicine and technology with stem cells are almost limitless.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 12, 2009, 06:16:39 AM
I thought you supported Operation Iraqi Freedom?  ???
There were two reasons for that and curing the worlds problems wasn't one of them.  I don't see the US as needing to go into Africa and dump a bunch of money into a problem that they could do themselves with other methods.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: loco on February 12, 2009, 06:25:46 AM
Embryonic stem cell research has yet to show any promise, even though it has been privately funded in the US and funded in other countries. 

Adult stem cell research on the other hand has already shown promise time and time again, as it did in this one case.

Nobody opposes adult stem cell research.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 12, 2009, 07:11:11 AM
There were two reasons for that and curing the worlds problems wasn't one of them.  I don't see the US as needing to go into Africa and dump a bunch of money into a problem that they could do themselves with other methods.

Again, Cap, there are one million americans with HIV.

If there is a cure that can save Americans lives, wouldn't you support it?
Title: Re: Man appears free of HIV after stem cell transplant
Post by: MCWAY on February 12, 2009, 07:57:58 AM
Embryonic stem cell research has yet to show any promise, even though it has been privately funded in the US and funded in other countries. 

Adult stem cell research on the other hand has already shown promise time and time again, as it did in this one case.

Nobody opposes adult stem cell research.

And, contrary to Beserker’s claims, there’s no religion standing in the way of scientific process.

In fact, one company that works with baby teeth to get stem cells is run by a devout Christian, Dr. Robin Crossman.

http://www.answersingenesis.org/articles/am/v2/n1/babytooth (http://www.answersingenesis.org/articles/am/v2/n1/babytooth)

http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome (http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome)

http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome (http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome)
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 12, 2009, 08:54:53 AM
Again, Cap, there are one million americans with HIV.

If there is a cure that can save Americans lives, wouldn't you support it?
Aside from children born with AIDS, transfusions, etc there are a lot of those that could have been prevented.  AIDS is preventable if you are not dumb.  I don't feel bad for junkies and degenerates that put themselves in a bad situation.  Wrap your tool, get tested, and don't whore around
Title: Re: Man appears free of HIV after stem cell transplant
Post by: loco on February 12, 2009, 04:34:06 PM
And, contrary to Beserker’s claims, there’s no religion standing in the way of scientific process.

In fact, one company that works with baby teeth to get stem cells is run by a devout Christian, Dr. Robin Crossman.

http://www.answersingenesis.org/articles/am/v2/n1/babytooth (http://www.answersingenesis.org/articles/am/v2/n1/babytooth)

http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome (http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome)

http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome (http://www.cryotooth.com/cryotooth.com/default.aspx?sec=Home&cat=Welcome)

Thanks for the links, MCWAY!
Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 12, 2009, 04:35:49 PM
Aside from children born with AIDS, transfusions, etc there are a lot of those that could have been prevented.  AIDS is preventable if you are not dumb.  I don't feel bad for junkies and degenerates that put themselves in a bad situation.  Wrap your tool, get tested, and don't whore around

should we stop treating lung cancer because only *some* of those who suffer get it from second-hand smoke?

how about colon cancer, the main cancer than kills men.  Poor diet causes it.  Do we cease all research on it because, well, you shouldn't eat junk food?
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 12, 2009, 04:41:58 PM
should we stop treating lung cancer because only *some* of those who suffer get it from second-hand smoke?

how about colon cancer, the main cancer than kills men.  Poor diet causes it.  Do we cease all research on it because, well, you shouldn't eat junk food?
You can't compare cancer to AIDS IMO.  Cancer kills way more people and a lot of cancer patients get it from ways that are not preventable.  We should spend more money on cancer than AIDS.  I'm not saying to cease research but WE as a country should not spend a lot of money for other countries.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: 240 is Back on February 12, 2009, 04:48:18 PM
You can't compare cancer to AIDS IMO.  Cancer kills way more people and a lot of cancer patients get it from ways that are not preventable.  We should spend more money on cancer than AIDS.  I'm not saying to cease research but WE as a country should not spend a lot of money for other countries.

smoking, junk food, alcohol, cheeseburgers, and many other things cause cancer.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: tonymctones on February 12, 2009, 05:14:40 PM
smoking, junk food, alcohol, cheeseburgers, and many other things cause cancer.
everything causes cancer these days bro, HIV is contractable only a few ways...cap has a valid point I think its great that they may made such progress in curing HIV but cancer should definitly be a much higher priority.
Title: Re: Man appears free of HIV after stem cell transplant
Post by: Cap on February 12, 2009, 05:36:52 PM
smoking, junk food, alcohol, cheeseburgers, and many other things cause cancer.
So if they don't practice proper health that's their problem.  There are many ways to prevent HIV and not nearly as many with cancer.  I don't feel bad for smokers and don't think they have the right to sue when they get sick. 

You can't compare AIDS here to AIDS there.  Aside from transfusions and children being born to infected mothers, it's pretty preventable on your own here.  Look at cancer, there are completely healthy people who suddenly develop brain cancer.  They didn't get that from fucking an infected cancer patient.