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Getbig Main Boards => Gossip & Opinions => Topic started by: musclepost on November 14, 2009, 12:03:06 PM
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http://www.newscientist.com/blogs/shortsharpscience/2009/11/muscular-monkeys-prompt-sports.html
Linda Geddes, reporter
A gene therapy that appears to bulk up muscle mass and strength in monkeys - reported today in Science Translational Medicine - will undoubtedly raise fresh concerns about the potential for gene doping in sport.
We already know that some athletes use drugs like erythropoietin to increase the amount of oxygen their blood delivers, and steroids to bulk up muscle mass.
The big advantage with gene doping is that it should be harder to detect. That's because it's difficult to test for a protein that the body already produces, especially when its levels naturally vary between individuals - which might explain why some people are inherently better at sports than others.
In the new study, Janaiah Kota and colleagues at Nationwide Children's Hospital in Columbus, Ohio, used gene therapy to add extra copies of the follistatin gene into the leg muscles of monkeys. Follistatin has been previously shown in mice to block myostatin, a protein that decreases muscle mass, resulting in bulked up "mighty mice".
Monkeys injected with the gene also seemed to bulk up, and when Kota's team analyzed their leg muscles with a device that measures force, they found that the muscles injected with the follistatin gene were also stronger than normal muscles.
They hope the approach could eventually be used to treat the severe muscle weakness associated with neuromuscular disorders like muscular dystrophy and multiple sclerosis.
Indeed, the drugs companies Amgen and Wyeth are already experimenting with drugs called myostatin inhibitors in humans, with some promising early results.
Such studies have already prompted fears about the potential for myostatin inhibitors to be abused by athletes hoping to gain the competitive edge. If gene therapy can achieve similar outcomes in humans, such modifications will be even harder to detect.
The World Anti-Doping Authority has already prohibited the use of gene doping within their World Anti-Doping code, and while there is currently no hard evidence of athletes using gene doping to improve performance, there are strong suspicions that they will start doing so soon - unless someone figures out a reliable way of detecting it.
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Sign me up, I don't even care if it's testable.
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The way things are going I'm afraid that all kinds of competition, be it mental or physical will become futile, the winners being the ones who can afford the newest technology.
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Sign me up, I don't even care if it's testable.
I agree. Anything that can improve muscle size and strength without shutting down your own hormones (like steroids do)I'd be interested in. The whole..going through months of low testosterone and shrinking, having no sex drive and all that crap makes steroids suck. I want something that works without affecting your own hormones.
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I agree. Anything that can improve muscle size and strength without shutting down your own hormones (like steroids do)I'd be interested in. The whole..going through months of low testosterone and shrinking, having no sex drive and all that crap makes steroids suck. I want something that works without affecting your own hormones.
fuckin pussy
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When is the over the counter version coming to a GNC or bodybuilding.com? I'm looking forward to Muscletech's version, the "DONKEYKONG" line, the most extreme will be "SILVERBACK", with the tagline, "It makes your muscles grow like BANANAS!!! increase muscle size by 870%"
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fuckin pussy
No, just smart. Been there done that and looking for a better alternative than the 40 year old technology of steroids, which have too many drawbacks. Maybe that's why I look better than a lot of juicers and I've been clean since the late 80's.
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I agree. Anything that can improve muscle size and strength without shutting down your own hormones (like steroids do)I'd be interested in. The whole..going through months of low testosterone and shrinking, having no sex drive and all that crap makes steroids suck. I want something that works without affecting your own hormones.
yes, shutdown is what puts me off aas the most. It's in for a penny, in for a pound. By the time your body has returned to normal you start the next cycle and fuck things up again ??? terrible rollercoaster, better to be off all the time, or on all the time, in for a pound.
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Chimps can you help with testing?
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break out the monkey brains and wolf balls, wash it down with the urine of a bull.
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break out the monkey brains and wolf balls, wash it down with the urine of a bull.
is this suposed to make suddenly one an "alpha male"?
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is this suposed to make suddenly one an "alpha male"?
yes it's the new breakfast of champions. guaranteed to produce a master race.
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Someone got pictures of those monkeys? I couldn't find them
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is this it.
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is this it.
That's not Kai Greene