Getbig.com: American Bodybuilding, Fitness and Figure
Getbig Bodybuilding Boards => Steroids Info & Hardcore => Topic started by: st@nco on January 24, 2006, 03:24:12 PM
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Has anyone used this product for this purpose?
Only a very mild case of gyno that has been with me since puberty. A friend of mine said he used it for PCT and claimed that it helped with his.
Anyone used it? If so, did it work?
Does anyone know of any other similar products that actually work?
If I were to use XT is it best to use it on its own or coupled with other products?
Any advice would be appreciated.
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If you've had gyno (and I mean real gyno) since puberty, then nothing short of surgery will take care of it.
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: J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):27-34.
Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology.
Mandava U, Kirma N, Tekmal RR.
Department of Gynecology and Obstetrics, Emory University, 4217 Woodruff Memorial Building, 1639 Pierce Drive, Atlanta, GA 30322-4710, USA.
Our recent studies have shown that overexpression of aromatase results in increased tissue estrogenic activity and induction of hyperplastic and dysplastic lesions in female mammary glands and gynecomastia and testicular cancer in male aromatase transgenic mice. Both aromatase mRNA and protein are overexpressed in transgenic mammary glands and its expression is not limited to epithelial cells. However, it is more in epithelial than in stromal cells. Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated with very low concentrations of the aromatase inhibitor, letrozole. Low concentration of letrozole had no effect on normal physiology as indicated by no significant change in the circulating levels of estradiol and follicle stimulating hormone as well as no change in estrogen responsive genes such as the progesterone receptor and lactoferrin in the uterine tissue. These observations indicate that the expression of aromatase in both epithelial and stromal cells can influence the complex interactions of biochemical pathways leading to mammary carcinogenesis and that the aromatase inhibitor, letrozole can be used as chemopreventive agents without affecting normal physiology.
PMID: 11850204 [PubMed - indexed for MEDLINE]
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In medical studies, abrogated means that the progression can be stopped--not reversed.
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In medical studies, abrogated means that the progression can be stopped--not reversed.
Good point.
I don't think anyone said that an AI would reverse existing gyno.
If it's granulated gyno it's there to stay until surgery is performed.
DIV