I wouldn't say any are irritating. If 2, 3, and 4, are true, i.e. verified statements of fact, then why would they bother me?!
As for 1, I cannot assume it is 100% true since it cannot be verified. If someone said that to me, I would be somewhat amused, then walk away as they continue to shout on the sidewalk and hold up their cardboard signs of "The end is nigh" or "Worship God or else He will KILL you"...