We know a few things about NCAA Championship-level wrestlers:
1. They can't easily be taken down.
2. They have exceptional balance.
3. They know the importance of conditioning and endurance.
4. They have a deep understanding of positioning.
5. They have superior takedown abilities.
6. They have superior intestinal fortitude (they don't quit!).
So if you factor in Brock's athleticism, his agility and his strength, you have a guy with the makings of an MMA monster.
The biggest wildcard with wrestlers is their ability to take a punch. In MMA, everyone gets clocked. Some wrestlers like Henderson have granite jaws and some like Couture have glass jaws. Lesnar will get hit and none of his abilities will help him if he can't take a shot.
That being said, look for the UFC to match Lesnar up with a non-puncher his first time out like Frank Mir and avoid a dangerous striker like CroCop.