If I take 1-50mg tablet a day will it be THAT much of a difference in the whole scheme of things as opposed to taking 2-25mg half tabs around 12 hours apart? I'm trying to do the latter but it's a huge PITA and more than half the time it reduces the tab to a powdery/chunky mess when I split it. If I was to dose once daily I'm thinking I'd take the tab around 5pm in the evening (getting ready for work) so that any immediate effect could be taken out on the wife when I get home from work around 1am. Would this be significantly inferior to divided doses? Thanks.