I know someone who is very overweight due to the head. She is a great girl and functional member of society. Known her for over a decade and heard a lot of conjecture about her losing weight over that time but ultimately, nothing has really managed to stick and she's probably bigger than she was when I met her.
If a loving family, drill sergeant mentality personal trainers, personal trainers with a more delicate approach, dieticians, physicians, husband, children, can't help.. who or what can?