Kratom goes Schedule I at the end of the month...

[Master Blaster]

Drunkard, Welcome to Getbig, where we start posts of with insults. I've even spoke about the Lortab issue in the past, it's nothing new. And Shizzo, I know you're kinda green but weed and lortabs don't make you hallucinate.  Pills can and will make you make bad decisions but not hallucinate. You obviously know nothing about them and weed for that matter. You sound like a D.A.R.E. representative basically meaning you don't know what you're talking about. I still love you though.

What's your thoughts on a weed/Lortab stack? What dosage?

[Necrosis]

Well you're wrong. Opium has caused wars and ruined people's lives. Kratom has not.

Kratom has ruined plenty of lives, where it is indigenous in particular. There are many kratom addicts. I agree it shouldn't be S1 but certain strains like red vein thai and the concentrates (30x plus) are drugs, strong ones at that.

If you take a good dose of kratom you are high, itchy etc.


Anything that impacts the opiod system (although a new drug was just trialed in rats) is addictive, it;s the best option as far as opiate type drugs go for addiction, tolerance etc some strains are stimulating while some are sedating, like oxycontin versus hydromorphone


If there was no opium, wars would be fought over Kratom, opium is better so is almost every opiate for pain. I think of it like a spectrum, kratom is good for pain but less addictive and as you increase anti-nociception you get more addictive shit. Methadone follows this idea.

MJ was also once schedule 1, I would say kratom is more problematic than MJ.

[muscleman-2013]

I've also used it in the past when I came off opioids. It helped on so many levels. Taking it away imo is an act of aggression or domestic terrorism. They know what it's used for and why. Taking it only makes more addicts to hard drugs and pharmaceuticals. Fucking assholes.

The entire fucking US government is involved in CONSTANT domestic terrorism.  This is just a twinkle in the ocean.

[liberalismo]

Kratom has ruined plenty of lives, where it is indigenous in particular. There are many kratom addicts. I agree it shouldn't be S1 but certain strains like red vein thai and the concentrates (30x plus) are drugs, strong ones at that.

If you take a good dose of kratom you are high, itchy etc.


Anything that impacts the opiod system (although a new drug was just trialed in rats) is addictive, it;s the best option as far as opiate type drugs go for addiction, tolerance etc some strains are stimulating while some are sedating, like oxycontin versus hydromorphone


If there was no opium, wars would be fought over Kratom, opium is better so is almost every opiate for pain. I think of it like a spectrum, kratom is good for pain but less addictive and as you increase anti-nociception you get more addictive shit. Methadone follows this idea.

MJ was also once schedule 1, I would say kratom is more problematic than MJ.

You really have no idea what you're talking about. No lives have been ruined in Thailand over Kratom except people who got put in jail over it. And red vein thai is just a type of Kratom sort of like Columbian is a type of coffee. It's not stronger or weaker. How do I know? I've used Kratom for 15 years.

[Kwon]

KRAKATOA

[Purge_WTF]

You really have no idea what you're talking about. No lives have been ruined in Thailand over Kratom except people who got put in jail over it. And red vein thai is just a type of Kratom sort of like Columbian is a type of coffee. It's not stronger or weaker. How do I know? I've used Kratom for 15 years.

 Which strain had the best nootropic effects?

[Griffith]

Kratom has ruined plenty of lives, where it is indigenous in particular. There are many kratom addicts. I agree it shouldn't be S1 but certain strains like red vein thai and the concentrates (30x plus) are drugs, strong ones at that.

If you take a good dose of kratom you are high, itchy etc.


Anything that impacts the opiod system (although a new drug was just trialed in rats) is addictive, it;s the best option as far as opiate type drugs go for addiction, tolerance etc some strains are stimulating while some are sedating, like oxycontin versus hydromorphone


If there was no opium, wars would be fought over Kratom, opium is better so is almost every opiate for pain. I think of it like a spectrum, kratom is good for pain but less addictive and as you increase anti-nociception you get more addictive shit. Methadone follows this idea.

MJ was also once schedule 1, I would say kratom is more problematic than MJ.

A friend once mixed up a combo of the red Thai kratom for me at correct doses, we drank it several times that day while we were out, I barely felt anything, I was slightly more relaxed but it did not impair my functioning in any way at all and could carry on with normal conversations etc.

[Necrosis]

You really have no idea what you're talking about. No lives have been ruined in Thailand over Kratom except people who got put in jail over it. And red vein thai is just a type of Kratom sort of like Columbian is a type of coffee. It's not stronger or weaker. How do I know? I've used Kratom for 15 years.

There are plenty of people addicted to Kratom, you being one of them obviously.

You are echoing my point brah, certain types have different pharmacology, some have clear MAO-B inhibition like red vein as they are stimulating. Certain types also have different alkaloids which lends to the dirty pharmacology it has, clearly some strains are stronger than others. What do you mean by stronger?

Using your analogy, some coffees are stronger than others, if we are talking methylxathine content, if we are talking anti-oxidant level, it's more broad.

Your analogy is flawed unfortunately broseph... caffeine has no endogenous ligand or system, it exerts it's effects via Adenosine antagonism and phosphodiesterase inhibition. Opoids and the endorphin system are endogenous, we produce endorphins. Because we have a whole system for opiates, multiple receptors with differing effects you can have quite a difference in pain relief , euphoria etc, the mu, delta and kappa receptors act differently, oxycontin has a different response versus hydromorphone. Kratom being a plant like Cannabis, can be sedating, a mix, stimulating, last long or short etc you my friend are wrong.

I didn't check anything I wrote so if you can be so kind to double check my statements for validity it would allow me some free time.

[Necrosis]

A friend once mixed up a combo of the red Thai kratom for me at correct doses, we drank it several times that day while we were out, I barely felt anything, I was slightly more relaxed but it did not impair my functioning in any way at all and could carry on with normal conversations etc.

Ya, I have tried most strains and some concentrates, I have really no tolerance for opiates with a few days of oxycontin for knee surgery to compare it to. I found the red thai as strong as oxy, I found the 30x stuff to be honestly far more euphoric than oxy. I had the itch, which is the histamine reaction.  I am half trolling wiggs because the earth is flat, kratom should be legal, it is addictive but is a better option.

Just look at the pharmacology of the drug.

It is mainly a MOR  agonist, depending on the affinity, partial versus full for example, paradoxical effects can occur. It can reduce pain, enhance euphoria and release gaba (what benzos effect) and means it's addicting, there is just no way around it. Other drugs that activate the receptor like morphine are addictive, kratom is slightly different but would have to be. The MOR's are in the periaqueductal grey mostly, it's going to be addictive.

You might just be a savage, have you tried other strains?

[Fuzzy Nuts]

How do you guys ingest this stuff.  I checked out a website in Canada and all they sell is incense, but they suggest the same effects.

Wacked out coworker was making it into a tea I think. Guy would be out on his feet, swaying heel to toe.

[Chidoman]

I have the red strain Maeng Da as a preworkout, one teaspoon only on workout days, been doing it for two years now, and find no need to have it on non workout days....shit tastes disgusting, but it works, just like Buckleys!

Best most intense workouts, with absolute focus!

[liberalismo]

Which strain had the best nootropic effects?

They're all similar in that sense.

[liberalismo]

There are plenty of people addicted to Kratom, you being one of them obviously.

You are echoing my point brah, certain types have different pharmacology, some have clear MAO-B inhibition like red vein as they are stimulating. Certain types also have different alkaloids which lends to the dirty pharmacology it has, clearly some strains are stronger than others. What do you mean by stronger?

Using your analogy, some coffees are stronger than others, if we are talking methylxathine content, if we are talking anti-oxidant level, it's more broad.

Your analogy is flawed unfortunately broseph... caffeine has no endogenous ligand or system, it exerts it's effects via Adenosine antagonism and phosphodiesterase inhibition. Opoids and the endorphin system are endogenous, we produce endorphins. Because we have a whole system for opiates, multiple receptors with differing effects you can have quite a difference in pain relief , euphoria etc, the mu, delta and kappa receptors act differently, oxycontin has a different response versus hydromorphone. Kratom being a plant like Cannabis, can be sedating, a mix, stimulating, last long or short etc you my friend are wrong.

I didn't check anything I wrote so if you can be so kind to double check my statements for validity it would allow me some free time.

You're just trolling now.

[Simple Simon]

There are plenty of people addicted to Kratom, you being one of them obviously.

You are echoing my point brah, certain types have different pharmacology, some have clear MAO-B inhibition like red vein as they are stimulating. Certain types also have different alkaloids which lends to the dirty pharmacology it has, clearly some strains are stronger than others. What do you mean by stronger?

Using your analogy, some coffees are stronger than others, if we are talking methylxathine content, if we are talking anti-oxidant level, it's more broad.

Your analogy is flawed unfortunately broseph... caffeine has no endogenous ligand or system, it exerts it's effects via Adenosine antagonism and phosphodiesterase inhibition. Opoids and the endorphin system are endogenous, we produce endorphins. Because we have a whole system for opiates, multiple receptors with differing effects you can have quite a difference in pain relief , euphoria etc, the mu, delta and kappa receptors act differently, oxycontin has a different response versus hydromorphone. Kratom being a plant like Cannabis, can be sedating, a mix, stimulating, last long or short etc you my friend are wrong.

I didn't check anything I wrote so if you can be so kind to double check my statements for validity it would allow me some free time.

Trolling shouldnt be you putting all the effort in, it sort of defeats the object.

[Necrosis]

Trolling shouldnt be you putting all the effort in, it sort of defeats the object.

so would say a shitty troll.