According to TMZ and other outlets, Christopher was surrounded by friends, family members and loved ones at the time of his death, which took place after he tried to kill himself on Saturday night.
He did so via an attempted hanging in jail.
Prison guards discovered Lawler in his cell outside Memphis.
He was taken to a hospital shortly afterward, where he remained in critical condition until late Sunday morning.
Lawler, who wrestled in the WWE under the name Grandmaster Sexay, was arrested earlier this month for DUI after leading cops on a wild and dangerous chase.
Police reported that Brian smelled of alcohol and had an open 12-ounce can of beer in his center console; they arrested him on the spot.