Whats up with site injections????

[bigmo6891]

i hear that you should always inject in the glute, but what are the benefits of injecting in other areas of the body? for example shoulder/bicep/chest

[Big_Tymer]

You shouldnt always inject in glutes, IMO rotating injection sites will help keep receptors in that area fresh as well as keeping scar tissue down to a minimum. 

But I doubt you would want to inject into your bi's.  Ive never tried it but im pretty sure it would hurt like hell, even with a slin pin.  glutes/quads/delts are great.

[candidizzle]

You shouldnt always inject in glutes, IMO rotating injection sites will help keep receptors in that area fresh as well as keeping scar tissue down to a minimum. 

But I doubt you would want to inject into your bi's.  Ive never tried it but im pretty sure it would hurt like hell, even with a slin pin.  glutes/quads/delts are great.

please elaborate on what you mean

[Big_Tymer]

please elaborate on what you mean

im not a medical doctor, its just my opinion.  Say you were using 700mg prop/week, and were injecting 1ml into each glute every other day.   It would be much better if you spread the injections out to your quads or delts.  Most people experience outstanding gains the very first time they use, I believe this is due to the fact that their body isnt accustomed to the hormones and their receptors are fresh and hungry for the gear.

[candidizzle]

im not a medical doctor, its just my opinion.  Say you were using 700mg prop/week, and were injecting 1ml into each glute every other day.   It would be much better if you spread the injections out to your quads or delts.  Most people experience outstanding gains the very first time they use, I believe this is due to the fact that their body isnt accustomed to the hormones and their receptors are fresh and hungry for the gear.

yeah, but you said "rotating injection sites will help keep receptors in that area fresh"

what do you mean

[Big_Tymer]

refer to the thread you made the other day about oversaturation.  we arent sure exactly what the limit is, but there will definitely be a point where you will see diminishing returns.

[candidizzle]

refer to the thread you made the other day about oversaturation.  we arent sure exactly what the limit is, but there will definitely be a point where you will see diminishing returns.

i understand that completely dude,


your dont get more steroids at the point of injection though dude

that is my point

you said rotate injection sites to keep receptors in that area fresh

its inaccurate is all

because AR at the injection site arent any more avtivated than AR in other places ...when using AAS

[G]

You shouldnt always inject in glutes, IMO rotating injection sites will help keep receptors in that area fresh as well as keeping scar tissue down to a minimum. 

But I doubt you would want to inject into your bi's.  Ive never tried it but im pretty sure it would hurt like hell, even with a slin pin.  glutes/quads/delts are great.

shooting in the bi's is not painfull at all , just use 25 or 27

[Big_Tymer]

i understand that completely dude,


your dont get more steroids at the point of injection though dude

that is my point

you said rotate injection sites to keep receptors in that area fresh

its inaccurate is all

because AR at the injection site arent any more avtivated than AR in other places ...when using AAS

inject 1ml into your left glut every single day in that glute only, and after 3-4 weeks see how good that area stays.

[Emmortal]

inject 1ml into your left glut every single day in that glute only, and after 3-4 weeks see how good that area stays.

I think the argument is just on the terminology you used when you said "receptors" which really isn't the best way to describe what you are trying to get across.  It's true, if you continously shoot oil into the same muscle it can cause problems with absorption because the oil has to be broken down and the ester metabolized, but saying this is due to receptors isn't really correct.

[Knowledge]

Logically, if you think about it the AAS enters into the blood stream regardless, therefore dispersing it through the body to other receptors.

[Knowledge]

Found an article that may be a good read it's 7 pages

The Absorption, Distribution and Excretion of Anabolic Agents

http://jas.fass.org/cgi/content/abstract/57/1/233   the full pdf is on the right side

Found this in the article as well to try and end debate, not to mention my logic is wrong...

""Anabolic agents pass freely into and out
of cells. Within the cells of the target tissues
they occupy specific receptors and their anabolic
activity is probably proportional to the
number of occupied binding sites. When all
of the sites are occupied, the receptors are
saturated and an increase in the concentration
of agent has no further effect. Thus, there is
an optimum or "threshold" cell concentration
of the anabolic agents that results in maximum
cell response and, ultimately, maximum increase
in physiologic response.""

[candidizzle]

Found an article that may be a good read it's 7 pages

The Absorption, Distribution and Excretion of Anabolic Agents

http://jas.fass.org/cgi/content/abstract/57/1/233   the full pdf is on the right side

Found this in the article as well to try and end debate, not to mention my logic is wrong...

""Anabolic agents pass freely into and out
of cells. Within the cells of the target tissues
they occupy specific receptors and their anabolic
activity is probably proportional to the
number of occupied binding sites. When all
of the sites are occupied, the receptors are
saturated and an increase in the concentration
of agent has no further effect. Thus, there is
an optimum or "threshold" cell concentration
of the anabolic agents that results in maximum
cell response and, ultimately, maximum increase
in physiologic response.""

but that doesnt really address the issue of AR on adipose, nor the effect of more androgens on gh and subsequently igf-1

as well "fully saturated" receptors would produce rather quick rate of prtoein synthesis and resulting a rather quick rate of increased number of AR

[Knowledge]

Another article worth reading that may help in addressing your questions, I haven't finshed it yet, but.....

http://jcem.endojournals.org/cgi/content/abstract/76/4/996  Full PDF on right again...

Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty

[candidizzle]

cool ! thanks man

[no one]

please elaborate on what you mean

no kidding...

[Big_Tymer]

the first article knowledge posted pretty much sums up what im saying.