I would say that for "long term use" Nolvadex would be the safest, because it has positive effects on your lipid profiles and makes you actually feel good. For "dryer" look Arimidex is more effective, but many guys report side effects such as feeling sick and weak... Of course not all, but some. In addiction to these two there are countless of other products to choose from, you just have to decide whether you want to use a SERM or an AI...