I was on Accutane in college and although I got some crazy sides after a few months I was all clear. They did blood work before I started and I think monthly during treatment to check liver and kidney function.
I tolerated it well and it worked.
Some guys can take boatloads of orals and get no skin effects at all, others can simply look at a 200ml pin of HRT Test Cypionate and feel the glands in their back start acting up.
Accutane works wonders but is one of the roughest drugs you can take. At the minimum, be prepared to have sun ultra sensitivity, constantly sore joints, and you will always have to carry around a tube of vasoline for the inside your nostrils to prevent the dryness from giving you a full-time bloody nose. Liver values will shoot through the roof too, making a perfect addition for an already toxic stack of oral steroids. Getbigger drug for sure.