I like agonist/antagonist supersets for middle aged female clients. Bench/Row, Overhead Press/Pulldown, Deadlift/decline situps. Makes time more efficient and can get a lot of work done in a half hour. That being said, I never use them for my personal workouts other than the occasional chest/back day Arnold style.
As has been mentioned, rest-pause, dropsets, forced negatives are far superior for hypertrophy.
