A buddy of mine back in the 90's had a son who was growth hormone deficient, the child showed a far below average growth pattern. The Dr. prescibed GH for the child, after various tests. Today he is still a bit shorter than his peers, but according to his medical records, he did show average growth patterns while on the GH therapy.
I know of a ceratin IFBB Pro bodybuilder, who was getting their jaw size-jaw- line decreased by surgery....rumor stated, but their are some amazing before-after pics with a huge difference....