I don't think anyone really knows the body well enough to advocate such complex schemes as falcon is laughing at. People know many different ways to get big. When it comes to finding the "optimal" way, though, experts tend to develop theories that are simply unsupported by their observations.
All the studies so far aren't enough, aren't even 1% enough, to justify sort of training advice that is believed as dogma by countless experts and coaches the world over.
Ask one expert who believes he knows the optimal way to get you big / fast / strong etc. to get you there and he probably can. Ask another, who just as firmly believes many things which contradict the first, and he probably can too.
The health and fitness world is not known for attracting intelligent people, and yet you can find countless supposed experts in every corner who have somehow synthesized the bits and scraps of scientific research that exist into a perfect system that coordinates things down to the last rep. Give me a break.

Everyone who can write up a program to the last rep, percentage point of max, and second of rest... well, his reach has exceeded his grasp. These programs can be good guidelines, but taken as a total substitute for one's instincts as they so often are... that's a mistake.