gh affects (or effects? fuck I never get it right) some guys differently.. some guys who are heavy users don't get the huge skull (dorian, flex) and some guys who are light users get the mushroom-skull (cormier, dillett, even though he wasn't a light user)... some guys get a huge jaw (cutler and kai... even tito Ortiz).
nassers skull was always large, but didn't seem to get larger as the years of gh went on... and Nasser was the one to tell me that gh was the only thing that kept him growing, that he 'hit the limit' with AAS years ago (and this was 14 years ago).
I think the big, fatty hands are a results of gh + insulin, as gh alone (with aas) doesn't always do it.