Author Topic: Parkinson`s  (Read 6250 times)

Primemuscle

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Re: Parkinson`s
« Reply #25 on: June 01, 2015, 10:49:16 AM »
Parkinson's is no picnic from what I've read. Michael J. Fox is a trouper to have maintained an acting career through out his ordeal.

Necrosis

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Re: Parkinson`s
« Reply #26 on: June 01, 2015, 11:17:27 AM »
* breaks out dictionary and thesaurus *     ???

Parkisons=bad :D

Van_Bilderass

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Re: Parkinson`s
« Reply #27 on: June 01, 2015, 01:33:00 PM »
Parkisons=bad :D

Necrosis, what's your take on Humanofort and the research?
What do you think of the article in the OP?

Necrosis

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Re: Parkinson`s
« Reply #28 on: June 01, 2015, 04:44:10 PM »
Necrosis, what's your take on Humanofort and the research?
What do you think of the article in the OP?

The original article contains numerous errors of medical terminology and is purely ridiculous as they used no measures that are repeatable, what does 80% improvement mean?

The other studies are poor, one even said that the people served as their own controls, lol.


forillagorilla

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Re: Parkinson`s
« Reply #29 on: June 01, 2015, 04:47:33 PM »
There are a few really educated posters over at PM on the subject - but Animals board and Underground (queefers site) are the best place for info

Thong Maniac

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Re: Parkinson`s
« Reply #30 on: June 01, 2015, 06:39:04 PM »
feel for the guy,,hard to watch him interviewed/tv,,he had a show 2 yrs ago I think got cancelled 1 season.shame..he has a grown family and good people around him ..in his prime was tough to get it and watch it progress..

Sat next to a guy on a plAne, he was/is a doctor and had terrible shakes he couldnt control. Very weakened, but his mind was still on point. It was hard because i wanted to help him get in and out of seat but u never know if he is too prideful and doesnt want help. Chatted with him about unrelated stuff, was a nice guy and too young. Really shitty disease

biceps

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Re: Parkinson`s
« Reply #31 on: June 06, 2015, 11:42:36 AM »

biceps

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Re: Parkinson`s
« Reply #32 on: June 06, 2015, 11:54:48 AM »
The original article contains numerous errors of medical terminology and is purely ridiculous as they used no measures that are repeatable, what does 80% improvement mean?

The other studies are poor, one even said that the people served as their own controls, lol.



He was not able to go up stairs or down stairs with out help, now he is able to go up and down with out help. It is a medical food for people suffering with PD, is not a drug and it not a cure is to help people with PD to have a better life and is nothing wrong with that. They have now over 20 people signed up voluntary for the study.    

biceps

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Re: Parkinson`s
« Reply #33 on: June 06, 2015, 12:00:52 PM »
I think Humanofort is mostly a scam, Emeric  :D

Romania

One patient

Self reported "80% improvement" in symptoms, in this "last stage" patient

Product is available as a relatively cheap "vaccine grade" supplement, sold by the doctor
doing this "study".

Come on  ::) :D



Of course because you never try it. Here a study conduct on dogs, dogs have no placebo effects.

Scientific research has clearly indicated[1] that the natural agents of
the DOGtor Rx formula help production of cortisol and insulin 
in the physiologically optimal amounts, which naturally alleviates
several common dog diseases.
   


This document was written by Dr.Robert Gipper and has been professionally translated from Hungarian to English.
 
Among the above mentioned beneficial effects of this formula, personally I was most interested in cases where the disease is a result of hormone imbalance. As you know, the alternatives are scarce or very expensive in the treatment of these.   



•   Diabetes mellitus

Patient No. 1: 4 year old female Poodle. In this fortunate situation, diabetes was diagnosed early, no major complications were present, and the blood sugar level was not excessively high either (12 mmol/l).
We started giving her the Eukanuba weight diabetic control feed, and the natural growth factors supplement (2x50 mg).
The blood sugar level was normalized within a few days and remained unchanged for the next four weeks.
   

Patient No. 2: 6 year old male, mixed breed, who has been suffering from diabetes for a longer period of time, and has been given insulin twice a day. After two weeks of taking the natural growth factors supplement (2x50 mg), the insulin could be reduced to half, after four weeks to one quarter of the original amount. It has been six weeks of treatment now, and the dog is not being given insulin at all.


Patient No. 3: 10 year old female Rottweiler, who has been receiving insulin-therapy for a while, and there was no improvement in her condition even after spaying.
She has been taking the natural growth factors formula (2x150 mg) for the past six weeks, and we only need to give half of the original daily dose of insulin now. We achieved this result around the 4th week of treatment, but our attempts to reduce this amount any further have been in vain so far: if we gave a dose smaller than half of the original, the blood sugar level invariably bounced back up too high. 

•    Diabetes insipidus

Patient No. 1: 8 year old male Fox Terrier, who has been suffering from this type of diabetes for a longer period of time, and has been given Minirin (desmopressin). He has been taking the natural growth factors formula (2x50 mg) for four weeks, and at this point he only needs one quarter of the original Minirin dose to show no symptoms, that is, he does not drink and urinate excessively.

Patient No. 2: 9 year old Dachshund mix. This is a recent case, he has been taking the natural growth factors formula (2x50 mg) since the onset, for 6 weeks. He drinks significantly less water and he does not have urinary incontinence problems any more, but he is not asymptomatic yet.

•   Cushing’s disease

Patient No. 1: 10 year old female Dachshund. In her case, the disease has been diagnosed some time ago, she has been taking Nizoral pills (Cetoconazole) to reduce the symptoms, and has been fed Eukanuba Light feed to lose the excess weight. At this point, she has been taking natural growth factors formula (2x50 mg) for six weeks, she is not on Nizoral any more, but we are continuing with the lower calorie diet. Right now her water intake and urination are normal, she has lost a considerable amount of weight, and we observed a significant improvement in her fur and skin condition. 

Patient No. 2: 11 year old male, mixed breed. He is a recent case, he has been taking Vetoryl pills and the natural growth factors formula (2x50 mg) since the onset of the disease, that is for four weeks. By the end of the fourth week, he only needs a quarter of the Vetoryl amount to make it through the night without having to be taken outside to urinate. The owner cannot afford to put him on a special feed, so all we could do to change his diet was that they limit the amount of food intake at home, and improve the quality of that food as much as they can.

Patient No. 3: 7 year old female, West High Terrier. She has been suffering from constant eczema issues, and was undergoing Prednisolone therapy coming from a different clinic. She has just recently come to us for treatment. The Cushing’s disease was a result of the continuous doses of glucocorticoid, and she was showing the classical symptoms. As the first step, we ran allergy tests which revealed nutritional problems. We changed her diet to the Eukanuba Dematosis feed, and ever since the onset of the disease three weeks ago, she has been taking the natural growth factors formula (2x50 mg). We stopped giving her Prednisolone altogether, but in the beginning of our treatment program we used skin soothing shampoo and antihistamine to reduce itching. As far as water-intake and urination, her condition has improved, but she is not asymptomatic yet, her weight remained unchanged. There has been a visible improvement, however, in her fur and skin condition already.


•   Hypothyroidism


Patient No. 1: 10 year old female Boxer. When she came to my clinic, she was considerably underweight, and showed symptoms of alopecia, hyperpigmentation, and shedding. The results of the blood test suggested hypothyroidism. We also detected mammary tumor and cystic transformation of the ovaries. We performed the necessary surgeries (ovarihysterectomy, removal of tumoral mammary tissue), changed her diet to Eukanuba Senior, and started her on the natural growth factors formula (2x150 mg). After four weeks of treatment, her condition was significantly better, the shedding ceased, and there was a substantial improvement in her overall well-being.


It is important to note that in the above mentioned cases of hormonal imbalance, we doubled the dose described in the “directions for use”. Based on clinical experiences with this formula in the US, they recommend a higher dose in similar cases.


•   Idiopathic colitis

Patient No. 1: 7 year old Cane Corso. He came in with constant diarrhea and was in a very bad shape. Based on various laboratory examinations, idiopathic colitis was diagnosed.
At this point, his treatment regimen is determined as follows: Salazopyrin pills, Eukanuba Intestinal feed, and natural growth factors formula (2x150 mg, twice the normal dose). After four weeks of treatment, the consistency of the feces is better, and although the complete resolution to solid stool has not occurred yet, his condition visibly improved, his fur is becoming shinier, and he is happier and more playful than four weeks ago.


•   Other cases

In 10 cases, we gave the formula to dogs who were recovering from surgery, or who were in weak condition after an illness, and older dogs in poor physical condition. After 24-48 hours, there was a noticeable improvement in their mood and appetite. Their condition generally improved within two weeks, and the older dogs regained their youthful energy.

In 10 cases we treated dogs suffering from skin problems. While addressing the underlying causes, we also put the dogs on the natural growth factors formula.
In two weeks, after successful treatment of the underlying causes, generally their fur and skin condition also considerably improved.

In 10 cases we gave the formula to dogs with locomotor disorder. For various reasons, surgery was not an option for them, only symptomatic treatment was possible (i.e.: hip and elbow dysplasia, other arthritic conditions, etc.). Beyond pain relief, we gave them the natural growth factors formula instead of mussel extract. As a general conclusion, we can say that this treatment reduced the locomotor symptoms substantially better than previously used regimens. In four cases, we could stop giving pain relief pills after two weeks, they only take the natural growth factors formula now.

In two cases we gave the formula to dogs with persistent, recurring panosteitis. In addition to and following the usual treatment (antibiotics and non-steroids), continuous administration of the formula successfully prevented recurrence of the disease. 

To summarize the above, I am confident that the natural growth factors formula considerably improves the medical conditions stated in the indications. In the treatment of hormonal imbalance, this formula fills a prominent gap: in a lot of cases, we lack alternatives.
I am happy to recommend this product, because I believe it will be a useful formula in the everyday practice of numerous colleagues, not only as a supplement, but also in helping to address the underlying causes. The planned consumer price is very reasonable even for our not-so-wealthy clients, and that is something to consider in today’s world. 




Dr. Róbert Gippert
Lead Veterinarian
Kaposvár, Hungary



                           REFERENCES

1. Gippert R., Clinical experiences with natural growth factors in our Hungarian practice, Small Animal Practice Periodical 2008, 2nd issue, page 78.







Necrosis

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Re: Parkinson`s
« Reply #34 on: June 06, 2015, 04:12:17 PM »
He was not able to go up stairs or down stairs with out help, now he is able to go up and down with out help. It is a medical food for people suffering with PD, is not a drug and it not a cure is to help people with PD to have a better life and is nothing wrong with that. They have now over 20 people signed up voluntary for the study.    

Great.

Parkison's is a disorder of destroyed neurons in the mesocorticolimib, niagrosriatal, basal ganglia. This creates issues with movement as dopamine in the SA controls things like muscle tonicity, movement etc.

The treatment for this is dopaminergics, ie things that increase dopamine or pro-drugs of dopamine itself like L-dopa. Why not just use dopamine? it does not cross the blood brain barrier, the thing in your head that keeps the shit out, so you have to give a precursor, one that crosses the BBB and then converts to dopamine.. the drug L-dopa is born. One problem, L-dopa is decarboxylated peripherally and causes issues like vasoconstriction, inflammation, so they needed a decarb inhibitor.. the drug carbidopa was born. L-dopa works all on it's own and it's in a lot of things, like velvet bean for example, many supplements with mucuriens purea (sp?) have ample amounts of l-dopa. l-dopa unfortunately increases oxidation (the problem in the first place) so speeds up the issue while improving it concurrently.

There are quite a few compounds that have benefit in parkison's.

These guys could make something that would be helpful, I could think of many cocktails, ones with far better research then this. L-tyrosine is in there product, it works fleetingly as it's under enzymatic negative feedback and the enzyme down regulates making it useless. They have l-dopa in it as well, fair enough, without a PDCI the sides will be much worse.

Caffeine is likely in the mix, has plenty of research and makes perfect sense as it protects dopaminergic neurons from oxidation in all sorts of models. It also works clinically, however, tolerance makes it's use short lived which requires cycling.

Glutathione IV and inhalation have shown remarkable results, very brief as it's half life is short. You can raise glutathione very high via supplemental N-acetyl cysteine, which has literature for treatment of PD, namely slowing progression. Green tea has numerous studies, it increases dopamine via catecholmethyltransferas e inhibition or COMT, the effect is clinical and pronounced. The chief issue with this is that those on l-dopa can't tolerate it at all, making it useful in those who can't tolerate l-dopa.

some mitochondrial nutrients like coq10 and PQQ have shown promise, mainly via there role in redox metabolism. There is more to it then dopamine, things like alpha-synuclein buildup, green tea does a good job of this.

None of this will cure them, they will progress, you can slow it, improve it drastically (I have seen L-dopa make new people) but there is no cure. The genes that regulate oxidation, growth in the neurons, apoptosis in them etc are fucked, they are downregulated, the problem will just keep going, slowly incrementally worsening. It could be intermittent symptoms, a "flare" shaking, tremor etc, or straight progression and loss of function.

It may be ok, but self blinded studies by the guys selling it and case controls on various animals for various diseases (the causes of which couldn't be more distinct) won't do it. I say this not being a girl, but these guys are not being legit.







biceps

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Re: Parkinson`s
« Reply #35 on: June 06, 2015, 06:28:21 PM »
Great.

Parkison's is a disorder of destroyed neurons in the mesocorticolimib, niagrosriatal, basal ganglia. This creates issues with movement as dopamine in the SA controls things like muscle tonicity, movement etc.

The treatment for this is dopaminergics, ie things that increase dopamine or pro-drugs of dopamine itself like L-dopa. Why not just use dopamine? it does not cross the blood brain barrier, the thing in your head that keeps the shit out, so you have to give a precursor, one that crosses the BBB and then converts to dopamine.. the drug L-dopa is born. One problem, L-dopa is decarboxylated peripherally and causes issues like vasoconstriction, inflammation, so they needed a decarb inhibitor.. the drug carbidopa was born. L-dopa works all on it's own and it's in a lot of things, like velvet bean for example, many supplements with mucuriens purea (sp?) have ample amounts of l-dopa. l-dopa unfortunately increases oxidation (the problem in the first place) so speeds up the issue while improving it concurrently.

There are quite a few compounds that have benefit in parkison's.

These guys could make something that would be helpful, I could think of many cocktails, ones with far better research then this. L-tyrosine is in there product, it works fleetingly as it's under enzymatic negative feedback and the enzyme down regulates making it useless. They have l-dopa in it as well, fair enough, without a PDCI the sides will be much worse.

Caffeine is likely in the mix, has plenty of research and makes perfect sense as it protects dopaminergic neurons from oxidation in all sorts of models. It also works clinically, however, tolerance makes it's use short lived which requires cycling.

Glutathione IV and inhalation have shown remarkable results, very brief as it's half life is short. You can raise glutathione very high via supplemental N-acetyl cysteine, which has literature for treatment of PD, namely slowing progression. Green tea has numerous studies, it increases dopamine via catecholmethyltransferas e inhibition or COMT, the effect is clinical and pronounced. The chief issue with this is that those on l-dopa can't tolerate it at all, making it useful in those who can't tolerate l-dopa.

some mitochondrial nutrients like coq10 and PQQ have shown promise, mainly via there role in redox metabolism. There is more to it then dopamine, things like alpha-synuclein buildup, green tea does a good job of this.

None of this will cure them, they will progress, you can slow it, improve it drastically (I have seen L-dopa make new people) but there is no cure. The genes that regulate oxidation, growth in the neurons, apoptosis in them etc are fucked, they are downregulated, the problem will just keep going, slowly incrementally worsening. It could be intermittent symptoms, a "flare" shaking, tremor etc, or straight progression and loss of function.

It may be ok, but self blinded studies by the guys selling it and case controls on various animals for various diseases (the causes of which couldn't be more distinct) won't do it. I say this not being a girl, but these guys are not being legit.








This Drs are legit, the problem they have is that is a medical food not a drug, so is very hard to fine any clinics to supply patients for a study. So now they have over 20 voluntary and more are signing up.   
                                                                                                                                                                                                                                                                        The medical food contains:
N-Acetyl L- Cysteine 1g*
Branch Chain Amino Acids 1g*
L-Leucine
L-Isoleucine
L-Valine
Mucuna pruriens 1g*
Choline Bitartrate 1g*
Oligopeptide 1g*
(Gallus Gallus)(Chicken)MIR-133b, MIR-146a

The reason I posted the studies on dogs is because  Humanofort has demonstrated a wide range of benefits for different people, and animals in varying parts of the body.

We have embarked on new frontiers in pharmaceutical therapeutics, nutritional significance and the dietary algorithms for understanding disease causation and the corrective nutritional dietary programs for disease prevention. The conceptual validation, using scientific research and confirmation that nutrients are the key to genetic (genomic) signaling is now a foundational reality. Dietary intake is responsible for not only supplying the body’s cellular machinery with a fuel substrate but with the correct signaling information machinery to its own genomic core; to allow the variable genetic coding the ability to respond through transcription with up-regulation, down-regulation, inhibition and/or stimulation, establishing end-organ responses.

One may draw and analogy with the amazing multi-signaling component of Humanofort wherein the natural growth factors are believed to manifest new and exciting signaling capacities.  One may make an analogy wherein the ingredients in Humanofort are thought to act as “ligands” to receptors or intra-cellular and intra-nuclear sensors.  As a result of these actions we can reasonably propose that a complex cascade of reactions occurs creating healthy aging, genetic balance and disease prevention in the organism. 

Humanofort is believed to act as an adaptogenic product (i.e. a product that modifies the equilibrium of hormones secreted by adrenal cortex).  In this manner Humanofort  support balance to the hypothalamus-pituitary-adrenal axis and the entire endocrine system in achieving homeostasis and efficient operation.  In turn the endocrine system may secrete hormones at optimum levels resulting in improved cellular signaling. This improved cellular signaling may result in cellular rejuvenation and ultimately translate to optimal health longevity and restoration of youthful vitality to the body.

Humanofot is reach in miRNA and has naturally occurring many Growth Factors one of them is FGF (Fibroblast Growth Factor).  While FGF is readily available in the human placenta, its availability to the human body diminishes over time and essentially vanishes as we age. Our body is incapable of producing its own FGF, so it must derive it from the food supply.
 
That is where Humanofort  fills a crucial, missing link in the human chain of life.

Research credits FGF with essentially reprogramming adult stem cells and amino acids in the body (which make up its natural repair tools) to travel to the areas that need it the most. Once there, these repair tools have the ability to integrate themselves with that particular body part. Their mission then becomes to repair and regenerate the cells and tissue in that location, wherever it is in the body.
Growth Factors are critical to anti aging hormones. In a clinical study entitled,"Biometric Analysis of Controlled Clinical Study for Growth Factor Formulation on Multiple Parameters of Aging Related Dysfunctions", Dr. M. Suarez and colleagues, Dr. Suarez reported that "clinical evidence demonstrates that the replacement of Growth Factors significantly reduced symptoms of aging".

Reference: Suarez, M., et al., "Biometric Analysis of Controlled Clinical Study For Growth Factor Formulation on Multiple Parameters of Aging-Related Dysfunctions", High Tech Research Institute, 2002.

1. Accelerated aging due to stress can adversely affect growth factor production, [such as BDNF/Brain Derived Neurotrophic Fator], and appear to be reduced perhaps to a greater percentage from the norm than bio-identical hormones due to mental and emotional stress.
2. As the body ages growth factor production often becomes reduced at a greater rate than other hormones. 
3. Humanofort Growth Factors are nutritional building blocks that support the human biological system to build new healthy tissue. While hormones, vitamin D, and exercise are necessary, they are only part of the equation. Emerging Medical Research has shown that the Growth Factors are actually in charge of cellular messaging and RNAi. These tiny clumps of amino acids called peptides are the key to anti aging. It turns out that the repair and replacement of a cell is under the direction of these peptides, not the hormones. Thus growth factors, like BDNF, are the actual cellular structural architects.
Why haven't you heard much about  growth factors?
1. Because the synthetic manufactured version of these peptides are not stable enough thus far to be mass produced and sold like bio identical hormones or vitamins.
2. Semi-stable, Non Bio-identical versions have  been produced, but not for general use. Bioidentical Hormone acceptance was clouded by the dangerous side effects resulting from use of Non Bioidentical Hormones.

Humanofort contains no bioidentical or non bioidentical hormones.

Is 2 new studies( submitted for publication) with values of Humanofort and its peptides components in different antioxidant assays and stimulating and protective effects of peptides from chicken embryo extract on probiotic bacteria.

Just in advance Humanofort out performed Glutathione in ABTS Radical Cation Scavenging Activity, Superoxide Anion Radical Scavenging Activity, and Hydroxyl Radical Scavenging Activity 50.62 ± 0.38 to 3.25 ± 0.02

I don`t know what is your background but I think that you are very smart man, I think we could have a very nice telephone conversation on this topic.



Necrosis

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Re: Parkinson`s
« Reply #37 on: June 07, 2015, 05:59:33 AM »
This Drs are legit, the problem they have is that is a medical food not a drug, so is very hard to fine any clinics to supply patients for a study. So now they have over 20 voluntary and more are signing up.   

Don't be fooled by that, having dr's sign on is not a sign of competency or ethical/sound research. They are making something which may help, is not special and they can profit from. I have several parkison's patients, I regularly read medical research, daily. I use something called pubcrawler which basically sends me the latest primary research on any topic I have inputed. The research you are posting doesn't appear to be peer reviewed, the animal studies are hard to extrapolate to humans, particularly as the subject number was 1 meaning it's an N=1 study, not much can be drawn from that. It's promising and indicates more research should be done, but it's controls are non-existant and they could have also been on prednisone or mirapax etc I don't know, the study is poorly done. Do you have stock in this company or are you trolling or are you asking for someone you know?
                                                                                                                                                                                                                                                                        The medical food contains:
N-Acetyl L- Cysteine 1g*
Right, makes sense, I would use it, it increases glutathione. the dosage is right as well.
Branch Chain Amino Acids 1g*
L-Leucine
L-Isoleucine
L-Valine
This is an odd inclusion, particularly because BCAA'S compete for the neutral amino transporter across the BBB, they block tyrosine, which is a rate limiter for dopamine synthesis. It would help fatigue by depleting serotonin, but BCAA'S appear to be anti-dopaminergic, antagonists, not what you want.

Mucuna pruriens 1g*
I will be honest, after seeing so much non-sense and bullshit research I glanced at the product as the claims are outlandish based on poor methodology with a blend of things, some of which could be doing nothing, some could be synergizing, some inhibiting, aminos do compete. This has L-dopa, so it's not medical food, it's a supplement and a compound with drug like effects. The fact that i could guess what was in this based on the claims etc is not looking good for a breakthrough.
Choline Bitartrate 1g*
cheap form of choline, increases DA and ACH, should have used citocholine
Oligopeptide 1g*
(Gallus Gallus)(Chicken)MIR-133b, MIR-146a

The research on this stuff is really poor, the guys studying it in every case are involved with selling it, there's a huge conflict of interest. They also make some major claims given the paucity of the data. In the study with humans serving as their own controls (doesn't work like that, outlandish proposition) they say the effects are long-lasting, how do they know this? HDL increase is not long lasting, you don't increase it and be done with it, it's dynamic.

The reason I posted the studies on dogs is because  Humanofort has demonstrated a wide range of benefits for different people, and animals in varying parts of the body.
They are not good studies is the issue. Not enough to draw any meaningful conclusion, the L-dopa and NAC would make anyone feel better, wheather it's healthy or good long term is the issue. Anything with L-dopa for any period of time is not a good idea unless sick, it will cause redox in your dopaminergic neurons (DA neurons) ultimately accelerating any disease process. Not to mention the peripheral shit your vasculature will go through.

We have embarked on new frontiers in pharmaceutical therapeutics, nutritional significance and the dietary algorithms for understanding disease causation and the corrective nutritional dietary programs for disease prevention. The conceptual validation, using scientific research and confirmation that nutrients are the key to genetic (genomic) signaling is now a foundational reality. Dietary intake is responsible for not only supplying the body’s cellular machinery with a fuel substrate but with the correct signaling information machinery to its own genomic core; to allow the variable genetic coding the ability to respond through transcription with up-regulation, down-regulation, inhibition and/or stimulation, establishing end-organ responses.

They are talking about epigenetics, in a round about way. Nutrition modifies the genome and gene expression/regulation, we know this, so does stress etc, the problem is all these factors are dynamic and concurrent such that simply taking this nutrient will activate this gene, or that nutrient, we could do that with genomics etc but it's not this easy. Think of it like a severed limb, you could increase growth factors via genes, you could increase collagen synthesis etc it wouldn't matter, the cause is long gone, the damage done, the morphology changed, you can't use you missing arm to open the door just like your dead neurons can't produce dopamine.

One may draw and analogy with the amazing multi-signaling component of Humanofort wherein the natural growth factors are believed to manifest new and exciting signaling capacities.  One may make an analogy wherein the ingredients in Humanofort are thought to act as “ligands” to receptors or intra-cellular and intra-nuclear sensors.  As a result of these actions we can reasonably propose that a complex cascade of reactions occurs creating healthy aging, genetic balance and disease prevention in the organism. 

Humanofort is believed to act as an adaptogenic product (i.e. a product that modifies the equilibrium of hormones secreted by adrenal cortex).  In this manner Humanofort  support balance to the hypothalamus-pituitary-adrenal axis and the entire endocrine system in achieving homeostasis and efficient operation.  In turn the endocrine system may secrete hormones at optimum levels resulting in improved cellular signaling. This improved cellular signaling may result in cellular rejuvenation and ultimately translate to optimal health longevity and restoration of youthful vitality to the body.

Lots of adaptogens, withania, rhodiola, ssris, leucine, isoleucine, ginseng etc. It helps, it won't achieve homeostasis, the human body isn't altered this easily and for good reason.

Humanofot is reach in miRNA and has naturally occurring many Growth Factors one of them is FGF (Fibroblast Growth Factor).  While FGF is readily available in the human placenta, its availability to the human body diminishes over time and essentially vanishes as we age. Our body is incapable of producing its own FGF, so it must derive it from the food supply.

oral ingestion of miRNA is a pretty pig claim, I would imagine your body would digest it into it's elementary peptides and sugars like Ribose adn utilize them. I don't chicken miRNA is able to massively alter human gene transcription, it's in eggs of all species it appears, we eat it all the time, it has to undergo digestion and make it through the HCL, it won't.
 
That is where Humanofort  fills a crucial, missing link in the human chain of life.

Yes, all those people before us, the cavemen, evolved lacking humanofort. It's some simple amino acids found in red meat a herb, a choine source and some egg

Research credits FGF with essentially reprogramming adult stem cells and amino acids in the body (which make up its natural repair tools) to travel to the areas that need it the most. Once there, these repair tools have the ability to integrate themselves with that particular body part. Their mission then becomes to repair and regenerate the cells and tissue in that location, wherever it is in the body.
Growth Factors are critical to anti aging hormones. In a clinical study entitled,"Biometric Analysis of Controlled Clinical Study for Growth Factor Formulation on Multiple Parameters of Aging Related Dysfunctions", Dr. M. Suarez and colleagues, Dr. Suarez reported that "clinical evidence demonstrates that the replacement of Growth Factors significantly reduced symptoms of aging".

No it doesn't, it's pluripotent molecule, but as you can see the Fibroblast gives away it's role in growth like Nerve Growth factor or Brain Derived neurotrophic factor, it's one of many, increasing it is not universally good, it is involved in wound healing, and direct administration of it in cystic fibrosis for example has no effect, again the genes are silenced, they are done, a disease process occurred/occuring.


Reference: Suarez, M., et al., "Biometric Analysis of Controlled Clinical Study For Growth Factor Formulation on Multiple Parameters of Aging-Related Dysfunctions", High Tech Research Institute, 2002.

1. Accelerated aging due to stress can adversely affect growth factor production, [such as BDNF/Brain Derived Neurotrophic Fator], and appear to be reduced perhaps to a greater percentage from the norm than bio-identical hormones due to mental and emotional stress.

Curcumin increases BDNF more the humanofort, SSRI's do it potently as well, it's not a cure all.
2. As the body ages growth factor production often becomes reduced at a greater rate than other hormones.
Agreed, it's aging more then just that decreases, so does MTOR, WBC, steroid hormones etc.
 
3. Humanofort Growth Factors are nutritional building blocks that support the human biological system to build new healthy tissue. While hormones, vitamin D, and exercise are necessary, they are only part of the equation. Emerging Medical Research has shown that the Growth Factors are actually in charge of cellular messaging and RNAi. These tiny clumps of amino acids called peptides are the key to anti aging. It turns out that the repair and replacement of a cell is under the direction of these peptides, not the hormones. Thus growth factors, like BDNF, are the actual cellular structural architects.
Why haven't you heard much about  growth factors?
1. Because the synthetic manufactured version of these peptides are not stable enough thus far to be mass produced and sold like bio identical hormones or vitamins.
2. Semi-stable, Non Bio-identical versions have  been produced, but not for general use. Bioidentical Hormone acceptance was clouded by the dangerous side effects resulting from use of Non Bioidentical Hormones.

Trust us, we said they are bad and "dangerous".

Humanofort contains no bioidentical or non bioidentical hormones.

Is 2 new studies( submitted for publication) with values of Humanofort and its peptides components in different antioxidant assays and stimulating and protective effects of peptides from chicken embryo extract on probiotic bacteria.

Just in advance Humanofort out performed Glutathione in ABTS Radical Cation Scavenging Activity, Superoxide Anion Radical Scavenging Activity, and Hydroxyl Radical Scavenging Activity 50.62 ± 0.38 to 3.25 ± 0.02

It would as it's a mixture of anti-oxidants namely NAC the thing I said increases glutathione more then supplementing glutathione. In what cell type? this is meaningless, how it behaves in the body and how it behaves in an in vitro study is a little different. If they used hepatocytes or myocytes the results would change. They are clearly just trying to sell their product, just using words without any thought.

I don`t know what is your background but I think that you are very smart man, I think we could have a very nice telephone conversation on this topic.

Thank you, I am a physician and do research in neuroscience and neuropsychiatric disorders (ADHD,ASD etc). No dick pics, I feel unclean after your last sentence.



Primemuscle

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Re: Parkinson`s
« Reply #38 on: June 09, 2015, 01:20:58 AM »
Do you think it possible for temporary acute anxiety to cause Parkinson's symptoms, such as uncontrollable shaking hand movements?

Necrosis

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Re: Parkinson`s
« Reply #39 on: June 09, 2015, 11:04:59 AM »
Do you think it possible for temporary acute anxiety to cause Parkinson's symptoms, such as uncontrollable shaking hand movements?

Yes, but not because of anything parkison's related, ie not do to cell death (neuron death of cells that produce dopamine), it's likely from excessive norepinephrine being released causing flight or flight. Could be hypoglycemia as well, which increases with stress as cortisol has the inverse effect of insulin.

El Diablo Blanco

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Re: Parkinson`s
« Reply #40 on: June 09, 2015, 11:55:13 AM »
The science on Parkinson's is a little shaky

Van_Bilderass

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Re: Parkinson`s
« Reply #41 on: June 24, 2015, 05:53:19 AM »
Late reply, but thanks for the input Necrosis.

And yes, 'biceps' is involved with selling Humanofort.

Dr Dutch

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Re: Parkinson`s
« Reply #42 on: June 24, 2015, 02:49:38 PM »
Parkinson's is a locust disease. Can lead up to depression and dementia too. Treatment after the earlier stages has psychotisch Side effects.
Please try not to get this one......
Says Dr Dutch