Kind of. Inefficient means more work is being done than is necessary. More work = More calories burned.
Well, no. There's nothing 'thermic' about sugar, hfcs, or any high GI carb. I think you're confusing nutritionally inefficient (poorly nourishing but high calorie) with metabolically inefficient (calorie content reduced by metabolic processes), and I'm pretty sure you're doing it to annoy me.
Look and see. There are tons of malnourished fat people lumbering around. There really is such a thing as empty calories. And if you're dieting it's real important to make good nutritional use of the calories you've allotted yourself.
If you just like yummy things then eat 'em up and tell everyone that you're a powerlifter. But a sage fellow here said years ago, and correctly, that if you haven't seen your abs in a few years then you're not a bodybuilder.
*meltdown intensifies*
And never mind about the bodybuilders. What about every performance athlete in the world? I'm sure you can find a story about someone eating a Big Mac but do you really believe Olympians (the real ones, I mean) are paying no attention to macros and micros? Are UFC guys KFC guys? Shit no. Or how about non athletes? Just coincidence that the lower classes who subsist on crap also look like crap, while the macrobiotic whole foods crowd are fitter and healthier?
Do an experiment. Eat clean for a month. Don't hem & haw and get lost in the minutiae. You know pretty much what that means. You won't be the worse off for it so what have you got to lose?