they do lose money quite often on big failures in drug trials.
I did a five year stint in pharmacy financial planning, and went through the period where the pharmacies were basically printing money during what they called the "sweet spot", when a drug would go generic, but the PBMs would over compensate since they were clueless to what the actual cost of the drug was, due to the odd nature of the business (manufacturers selling to wholesalers, wholesalers selling to pharmacies, manufactures kicking back rebates outside of the wholesaler's knowledge, so the "true" price wasn't known). Then I went through when that gravy train ended......right around the time lipitor was going generic.
I know the costs big pharma spends to get a drug to market, and how the drugs that make it are priced to recover the failures of others.
None of that absolves big pharma from what chaos is pointing out. Use Vioxx as an example.
While these companies have produced legit medications that have improved quality of life, they are not above corruption.
I personally cannot trust them after the covid vax. You feel it was all "the best we knew at the time"....I feel there was too much information withheld, and the messaging around efficacy, effectiveness, and side effects was piss poor.
