Colon Cancer Screening

[BB]

Eggxactly!



By the definition of the word, a "balanced" diet would be

33.3 % Fat
33.3 % Protein
33.3 % Carbs

Next Nutrition (Designer Protein) and Duchaine tried this as the Isocaloric Diet and sold a protein powder and book around it. It faded out quickly, then they moved to Body Opus (ketogenic, with weekend refeed).

[loco]

Next Nutrition (Designer Protein) and Duchaine tried this as the Isocaloric Diet and sold a protein powder and book around it. It faded out quickly, then they moved to Body Opus (ketogenic, with weekend refeed).

Interesting.  I didn't know that.

[BB]

Interesting.  I didn't know that.

Yeah, it was around for maybe a year. Here's the book that went with it if you're bored -

https://www.anasci.org/ebooks/Isocaloric_Handbook.pdf .

[Thin Lizzy]

In my opinion, protein should be 30%-35% minimum, especially as we age.

As for mixing carbs and fat evenly, that's a recipe for disaster.  Choose low fat, or choose low carb.  Can't go low with both at the same time, can't go high/moderate with both at the same time.

Maintaining independence, quality of life, and health is crucial for elderly adults. One of the major threats to living independently is the loss of muscle mass, strength, and function that progressively occurs with aging, known as sarcopenia. Several studies have identified protein (especially the essential amino acids) as a key nutrient for muscle health in elderly adults. Elderly adults are less responsive to the anabolic stimulus of low doses of amino acid intake compared to younger individuals.

However, this lack of responsiveness in healthy older adults can usually be overcome with higher levels of essential amino acid (EAA) consumption.

The addition of nonessential amino acids to a supplement containing EAA does not result in additional stimulation of muscle protein synthesis [27], indicating that the quality of the protein, or its amino acid profile, is a key determinant of the functional potential of protein in muscle health. This is supported by several studies demonstrating that the ingestion of milk proteins, compared with the ingestion of soy protein stimulates muscle protein synthesis to a greater extent after resistance exercise, owing to the higher content of EAA in milk protein [28,29,30,31]. The data from the Health, Aging and Body Composition study support these findings [31], showing that intake of animal protein (with greater content of EAA), but not plant protein, was significantly associated with the preservation of lean body mass over three years in older adults.

The discrepancies in quality between animal and plant protein sources go beyond the amino acid profiles. When the energy content of the protein source is accounted for, the caloric intake needed to meet the EAA requirements from plant sources of protein is considerably higher than the caloric intake from animal sources of protein [36]. This is important to consider since obesity, especially with aging, is a major public health concern. Obesity is the most predominant factor limiting mobility in the elderly.

The consumption of dietary protein consistent with the upper end of the AMDRs (as much as 30%–35% of total caloric intake) may prove to be beneficial, although practical limitations may make this level of dietary protein intake difficult. The consumption of high-quality proteins that are easily digestible and contain a high proportion of EAAs lessens the urgency of consuming diets with an extremely high protein content.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924200/

The percentage is dependent on total calories. If you lower total calories without raising protein the percentage will be higher.

IMO, people overthink this shit. Just don’t eat too much too often.

An ounce or two of protein one way or another or few percentage point difference in carb and fat intake is splitting hairs.

[JackTheRipper]

Just like the Vax, worthless. All these idiots getting a tube snaked up their asses yearly for nothing.



Screening procedure fails to prevent colon cancer deaths in large study, Life & Culture - THE BUSINESS TIMES

https://www.businesstimes.com.sg/life-culture/screening-procedure-fails-to-prevent-colon-cancer-deaths-in-large-study

man you´re a Jackass

[loco]

Just like the Vax, worthless. All these idiots getting a tube snaked up their asses yearly for nothing.



Screening procedure fails to prevent colon cancer deaths in large study, Life & Culture - THE BUSINESS TIMES

https://www.businesstimes.com.sg/life-culture/screening-procedure-fails-to-prevent-colon-cancer-deaths-in-large-study

I read a bit more about this study and I think the article above is misinterpreting the study and its results:

A major sticking point for experts who reviewed the study’s findings was that only 42% of the people in the new study who were invited to get colonoscopies actually went through with them.

"This is a flaw of randomized trials of cancer screening tests," said Wender. "They inevitably become trials of invitations to screen, not the test itself."

In fact, the results were actually quite good for the people in the study who got the colonoscopies — a 31% reduction in colon cancer risk and a 50% reduction in risk of dying from it, experts said.

“In order for a colonoscopy to be effective, you have to have it done,”

Ng agreed, saying, “Colonoscopy only works if you actually go through with it.”
https://www.nbcnews.com/health/health-news/need-colonoscopy-new-study-colon-cancer-screening-effectiveness-rcna51515


The actual study:

"In this randomized trial, the risk of colorectal cancer at 10 years was lower among participants who were invited to undergo screening colonoscopy than among those who were assigned to no screening."

Follow-up data were available for 84,585 participants in Poland, Norway, and Sweden — 28,220 in the invited group, 11,843 of whom (42.0%) underwent screening, and 56,365 in the usual-care group.

A total of 15 participants had major bleeding after polyp removal. No perforations or screening-related deaths occurred within 30 days after colonoscopy.
https://www.nejm.org/doi/full/10.1056/NEJMoa2208375

[loco]

The percentage is dependent on total calories. If you lower total calories without raising protein the percentage will be higher.


IMO, people overthink this shit. Just don’t eat too much too often.

An ounce or two of protein one way or another or few percentage point difference in carb and fat intake is splitting hairs.

Do you mean the total grams from each macro are dependent on total calories?  Whether or not you lower calories, target percentages remain the same.  That's the whole point of using percentages.

[loco]

Yeah, it was around for maybe a year. Here's the book that went with it if you're bored -

https://www.anasci.org/ebooks/Isocaloric_Handbook.pdf .

Thanks!

[Thin Lizzy]

Do you mean the total grams from each macro are dependent on total calories?  Whether or not you lower calories, target percentages remain the same.  That's the whole point of using percentages.

I’m saying with 2k calories 150g of protein will be 30%; in a 3k diet, the same amount of protein will be 20%.

From what I’ve seen most protein recommendations are based on bodyweight not percentage of calories consumed.

[loco]

I’m saying with 2k calories 150g of protein will be 30%; in a 3k diet, the same amount of protein will be 20%.

From what I’ve seen most protein recommendations are based on bodyweight not percentage of calories consumed.

Got it.

[GymnJuice]

Interesting info about the effects of insulin on fat storage.

Bodybuilder related at 10:55... 

[ThisisOverload]

Interesting info about the effects of insulin on fat storage.

I lost him at the localized fat storage.

Having known people who injected insulin multiple times a day for decades, complete nonsense.

Also, a "balanced" diet doesn't mean "equal parts".

It's a balance of the nourishment required for daily life.

Has nothing to do with muscle building or fat storage, it's based on "life" essentials.

However, it is flawed because carbs are not essential for life.

[IroNat]

I lost him at the localized fat storage.

Having known people who injected insulin multiple times a day for decades, complete nonsense.

Also, a "balanced" diet doesn't mean "equal parts".

It's a balance of the nourishment required for daily life.

Has nothing to do with muscle building or fat storage, it's based on "life" essentials.

However, it is flawed because carbs are not essential for life.

He said injecting in the same spot for long periods caused the growth.

These people must be diabetics.

Do diabetics always inject in the same spot everyday?

[loco]

I lost him at the localized fat storage.

Having known people who injected insulin multiple times a day for decades, complete nonsense.

Lipohypertrophy is a lump of fatty tissue under your skin caused by repeated injections in the same place. It's common in people with diabetes.
https://my.clevelandclinic.org/health/diseases/22928-lipohypertrophy

 

[ThisisOverload]

He said injecting in the same spot for long periods caused the growth.

These people must be diabetics.

Do diabetics always inject in the same spot everyday?

Like i said, never heard of it and been around diabetics all my life.

My uncle has been shooting Slin around his belly button for over 20 years. He looks completely normal.

They typically rotate in 3-4 places.

Saying it's "common" is very relative.

Why don't all these BBer's who shoot insulin 3-4 times a day have these problems?

[Humble Narcissist]

Lipohypertrophy is a lump of fatty tissue under your skin caused by repeated injections in the same place. It's common in people with diabetes.
https://my.clevelandclinic.org/health/diseases/22928-lipohypertrophy

 

There are some ugly ass bodies in this world.

[IroNat]

Apparently it is a real thing.

https://my.clevelandclinic.org/health/diseases/22928-lipohypertrophy

Lipohypertrophy is a lump of fatty tissue under your skin caused by repeated injections in the same place. It’s common in people with diabetes. Lipohypertrophy can affect your body’s ability to absorb insulin and cause serious complications. It’s important to rotate injection or pump sites, inspect the skin and use a new needle for each injection.

What is lipohypertrophy?

Repeated injections in the same area cause lipohypertrophy, which involves a lump of fatty tissue under your skin. The area may feel lumpy, firm or rubbery. It also may be somewhat numb.
Who might get lipohypertrophy?

Lipohypertrophy is common among people who need regular insulin injections or infusion to treat diabetes. It can also affect people who need medication injections for HIV.

Factors that increase your risk include:

    Failing to rotate or change injection or infusion (pump) sites regularly.
    Having a low body mass index (BMI).
    Reusing needles (they should only be used once).
    Using human insulin instead of analog insulin (created in a laboratory).

How common is lipohypertrophy?

The condition is common in people with diabetes, affecting as many as 64% of this population at some point.

[loco]

The condition is common in people with diabetes, affecting as many as 64% of this population at some point.

So it isn't complete nonsense, and it's very common given the fact that over 30 million Americans have diabetes, and more than 7 million of them require daily insulin while the rest will likely require it too as some point.

[Marty Champions]

I lost him at the localized fat storage.

Having known people who injected insulin multiple times a day for decades, complete nonsense.

Also, a "balanced" diet doesn't mean "equal parts".

It's a balance of the nourishment required for daily life.

Has nothing to do with muscle building or fat storage, it's based on "life" essentials.

However, it is flawed because carbs are not essential for life.

Tell that to someone on dialysis

[loco]

Tell that to someone on dialysis

"Dialysate, also called dialysis fluid, dialysis solution or bath, is a solution of pure water, electrolytes and salts, such as bicarbonate and sodium."
https://www.davita.com/treatment-services/dialysis/in-center-hemodialysis/what-is-hemodialysis

Adding glucose to dialysis solution is not only unnecessary, but it's likely harmful:

Hemodialysate solutions often contain high concentrations of glucose (up to 200 mg/dL). The historical reasons for the addition of glucose to the dialysate included: (1) aid in performance of ultrafiltration and (2) minimization of nutritional (caloric) losses during dialysis. However, recent experimental evidence supports the fact that exposure to high levels of glucose may be pro-inflammatory. Given the high morbidity and mortality associated with dialysis and its linkage to chronic inflammation, the routine use of glucose in the dialysate may warrant reexamination.
https://pubmed.ncbi.nlm.nih.gov/18394054/

[Rambone]

Most Getbiggers have their colon cancer screenings marked on their muscle hunk calendars with the date circled and underlined twice along with a giant smiley face

[SF1900]

Most Getbiggers have their colon cancer screenings marked on their muscle hunk calendars with the date circled and underlined twice along with a giant smiley face

Lmao! 

[ThisisOverload]

So it isn't complete nonsense, and it's very common given the fact that over 30 million Americans have diabetes, and more than 7 million of them require daily insulin while the rest will likely require it too as some point.

Name one person you know who has it.

64% get it based on this "study" and i have family members and been around hundreds of people with diabetes and it's never once been mentioned.

Is it like Covid?

[Humble Narcissist]

Most Getbiggers have their colon cancer screenings marked on their muscle hunk calendars with the date circled and underlined twice along with a giant smiley face

Just hope that tube is really small.

[loco]

“Keto” Molecule May Be Useful in Preventing and Treating Colorectal Cancer, Penn Study Suggests

April 27, 2022

A molecule produced in the liver in response to low-carb “ketogenic” diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

In the study, published in Nature, researchers initially found that mice on low-carb, high-fat ketogenic diets have a striking resistance to colorectal tumor development and growth. The scientists then traced this effect to beta-hydroxybutyrate (BHB), a small organic molecule produced in the liver in response to keto diets or starvation.

“Our findings suggest that this natural molecule, BHB, could someday become a standard part of colorectal cancer care and prevention,” said study co-senior author Maayan Levy, PhD, an assistant professor of Microbiology at Penn Medicine, whose laboratory collaborated with the lab of Christoph Thaiss, PhD, also an assistant professor of Microbiology. The study’s first author was Oxana Dmitrieva-Posocco, PhD, a postdoctoral researcher in Levy’s lab.

https://www.pennmedicine.org/news/news-releases/2022/april/keto-molecule-may-be-useful-in-preventing-and-treating-colorectal-cancer-penn-study-suggests