"Science". 
The typical supp "company" consists of finding out whatever substance is "hot" in the bb community right now, buying several kilos of it in raw powder form from China, hiring day laborers at minimum wage to stuff it into capsules, getting some fancy bottle labels printed up, and starting a website. I could run one of these operations out of my garage.
Nothing could be farther from the truth. I said the major players, not fools like Polumbo and the like. As I said, I usually work with mainstream companies such as Pepsi, but after working with a few of the large supplement companies, my opinion has changed on them. You could certainly run a supplement business from your garage, but it wouldn't be worth over 100 million bones.
The big supplement companies have labs, they spend a lot of money on RD and they are out to push the envelope when it comes to supplementation. Fat burners and pro hormones are good examples of this.
Do you know why a lot of supplement companies market like they do? Their hardcore audience is dumb. To them extremes are cool. Look at the "sport" of bb. It's based on extremes! Look at the more mainstream EAS ads....they are marketing their products much differently to mainstream consumers and athletes.