MM seems to be a class act. I don't know the profit margins on supp sales, but my guess is that they aren't too great, as you have to compete with online stores with zero overhead, and the mass store pics I've seen look very nice. Complementary goods sold in the store could scoot those up tho - clothing, exercise equipment, etc.
The risky thing about supplement sales is that they are non-essential. If the US does go into a recession (which is inevitable as we're possibly entering a 3rd war, and we keep borrowing), lots of things we do will be considered non-essential in the eyes of consumers. They'll always write checks for rent, gas, electric, food, and clothing. But for most people, things like creatine (and sadly for me, websites!) will often take the backburner til things rebound.
So have fun with it, keep us posted on the area so we can support ya should you start one!