Methylated pro-hormones & liver toxicity

[gendreau_neil]

I have a question for anyone sufficiently knowledgeable who cares to answer:

If Methylated pro-hormones are designed not to aromatize so quickly, assuming they cannot be broken down by the liver, why are methlyated pro-hormones more toxic?  Shouldn't methlyation protect the liver?  This seems to be a contradiction.  I don't get it...   

[trab]

I have a question for anyone sufficiently knowledgeable who cares to answer:

If Methylated pro-hormones are designed not to aromatize so quickly, assuming they cannot be broken down by the liver, why are methlyated pro-hormones more toxic?  Shouldn't methlyation protect the liver?  This seems to be a contradiction.  I don't get it...   

They (and REAL alpha-17 alkalated steroids & PHs) are made like that to survive "1st pass" thru the Liver.
The chemicals responsible for that are hard on the body, they cause liver stress. If you take Dbol, Drol, or even methylated PH's and your liver values DIDNT RISE - Your taking BUNK!

The danger of them is overstated, BUT to gain any significant benefits from even real steroid - You need keep blood level of it significantly elevated and steadily so. PH's just dont do that. Period. They will bounce the plasma blood concentration all over the place. Invitation to bad sides, and little to no gains, and possibly in worse shape after stop
(Lighter, weaker, fatter,Bitch tits,depressed) due to knock out Nat test.

Even Oral-steroid only cycles give limited gains for 1st timers at best. Forget PH's.
Injectables are the only healthy way to use any usefull amount of steroid for BBing or anything else.
That is if: Your product is sterile and same w/  inj method.

[Rimbaud]

They (and REAL alpha-17 alkalated steroids & PHs) are made like that to survive "1st pass" thru the Liver.
The chemicals responsible for that are hard on the body, they cause liver stress. If you take Dbol, Drol, or even methylated PH's and your liver values DIDNT RISE - Your taking BUNK!

The danger of them is overstated, BUT to gain any significant benefits from even real steroid - You need keep blood level of it significantly elevated and steadily so. PH's just dont do that. Period. They will bounce the plasma blood concentration all over the place. Invitation to bad sides, and little to no gains, and possibly in worse shape after stop
(Lighter, weaker, fatter,Bitch tits,depressed) due to knock out Nat test.

Even Oral-steroid only cycles give limited gains for 1st timers at best. Forget PH's.
Injectables are the only healthy way to use any usefull amount of steroid for BBing or anything else.
That is if: Your product is sterile and same w/  inj method.

Well said.

[busyB]

AND watch the alcohol consumption, preferably none while taking these ph. Booze and methly ph is a toxic coctail (no pun intended)

[Rimbaud]

I have a question for anyone sufficiently knowledgeable who cares to answer:

If Methylated pro-hormones are designed not to aromatize so quickly, assuming they cannot be broken down by the liver, why are methlyated pro-hormones more toxic?  Shouldn't methlyation protect the liver?  This seems to be a contradiction.  I don't get it...   

Like trab said they're designed for the compound to survive the liver, in a nutshell they protect the compound you're taking & not the liver.

[Rimbaud]

AND watch the alcohol consumption, preferably none while taking these ph. Booze and methly ph is a toxic coctail (no pun intended)

Excellent advice as well.

[gendreau_neil]

Thanks guys - I guess I had the tail waggin' the dog.  Now all I need is a fresh bowl of cold water - no alcohol please!

I totally agree with the comment concerning injectables - problem is, quality gear is difficult to come by these days.  We do what we can.  Meanwhile, my aggression and sex drive is still high so my T levels must not have sunk yet!  On the other hand, solid gains are more difficult to come by - I've been stuck at 5'11, 230 lbs, 8% BF for about 5 years now.  On the other hand, I've never done more than 1200 mgs per week with various injectibles.

[4thAD]

Good advice here from some very knowledgeable people! 

[SWOLETRAIN]

great info on this thread. Way to break down a very misunderstood subject.

[Rimbaud]

What people fail to realize is these methylated pro-horomones are just as dangerous or even more dangerous then methylated oral steroids (dbol, winny, tbol, anavar, etc). IMO - they're more dangerous because they often new compounds that haven't been studied long. At least people have been taking the others for over thirty years.

[Princess L]

What people fail to realize is these methylated pro-horomones are just as dangerous or even more dangerous then methylated oral steroids (dbol, winny, tbol, anavar, etc). IMO - they're more dangerous because they often new compounds that haven't been studied long. At least people have been taking the others for over thirty years.

                which you and other knowledgeable guys have echoed many times over. 

*sigh*

[busyB]

What people fail to realize is these methylated pro-horomones are just as dangerous or even more dangerous then methylated oral steroids (dbol, winny, tbol, anavar, etc). IMO - they're more dangerous because they often new compounds that haven't been studied long. At least people have been taking the others for over thirty years.

Agreed Rim and there will never be any studies because once the FDA tells a company to stop making that hormone, they tweak the stucture slightly and put out the next product. Some will not say methylated so watch the 17- versions (read label for actual chemical name). Too many PH users also believe what the label reads, "No Estrogen, Increase Libido," yada, yada....

I have seen guys grow boobs and have a bad ache on their right side (liver area) beaucse they abused or took these products wayyyy tooo long. Very, very short cycles is best with these and proper PCT.

[peroni]

Agreed Rim and there will never be any studies because once the FDA tells a company to stop making that hormone, they tweak the stucture slightly and put out the next product. Some will not say methylated so watch the 17- versions (read label for actual chemical name). Too many PH users also believe what the label reads, "No Estrogen, Increase Libido," yada, yada....

I have seen guys grow boobs and have a bad ache on their right side (liver area) beaucse they abused or took these products wayyyy tooo long. Very, very short cycles is best with these and proper PCT.

I'm doing a 6 week maxadrol cycle with liver care and a pct. I'll keep you posted on the results healthwise.

[Beener]

I have a question for anyone sufficiently knowledgeable who cares to answer:

If Methylated pro-hormones are designed not to aromatize so quickly, assuming they cannot be broken down by the liver, why are methlyated pro-hormones more toxic?  Shouldn't methlyation protect the liver?  This seems to be a contradiction.  I don't get it...   

AS FAR AS NO AROMATIZATION GOES, ALL LIES. You'll get gyno easier on pro hormones easier than real gear, and from personal experience, AI's didn't help for some reason as it did with normal gear.

stay away