Lots of people swear by them.
In many places it has become an “in” thing to do.
Penn & Teller covered the topic on their Showtime special Bullshit.
Basically, they claim that all the colonic does is flush from your intestine the same stuff that would come out soon anyway, and unless you have a problem, they’re probably not necessary – at least not as necessary as many folks deem them.
My take is that, as a precautionary measure, they can’t hurt.