Arimidex or Nolva during your cycle? Wich is better and why. I know that Nolva is an anti-e, and adex is an AI, but wich would be more beneficial to run during my cycle? I have heard some new evidence that the decrease in IGF-1 reported with nolva use, is only in circulating blood levels and not actually a marker of the body's total IGF-1
It's a pick your poison, MCat.
Both have drawbacks.
Arimidex is stronger, though negating 85% of all estrogen in the body has a negative effect on the HDL/LDL ratio.
Nolvadex, being an anti-estrogen, only fills the estrogen receptors, but doesn't prevent aromatization, meaning more estrogen is present in the body just waiting to fill those receptors when they become available. The changes in blood levels of IGF-1 are only transitory and don't reflect the true total in the body, this is true.
I would go with Arimidex on cycle.
Nolvadex for PCT.
DIV