Here is a question and answer in which one authority has a different take than my post above (note that he discusses the acidity issue, but not the fructose versus other sugars issue, as such I
still say avoid the grapefruit juice/creatine combo):
Question: "Regarding the "how to take it", I've always thought that it was the asorbic acid (vitamin C) in juice that you want to avoid with creatine. In that case grapefruit juice and orange juice would be bad but most grape juice would be ok."
Answer: There is nothing wrong with taking creatine with grapefruit juice, orange
juice, or any Vitamin C containing product. The pH of the stomach is
approximately 2, which is just as acidic, if not more acidic, then these
juices. If creatine makes it through the stomach just fine, mixing it
briefly into juice is not going to cause any problems.
James Krieger
Graduate Assistant, Exercise Science
Washington State University
Webmaster, WSU Strength and Conditioning
http://www.weightsnet.com/weights/issue/2657#Anchor1