METFORMIN STOP FAT LOSS??????????

[bea]

step furthermore in the knowledge of the mechanism of action(share) of biguanides
Published in the magazine(review): therapeutic Medicine Endocrinology and Reproduction. January-February, 2002. Volume 4Numéro 1,
Author (s): Pierre Bougnères, Philippe Chanson
If we know well the effect anti-diabetic of biguanides, we know less well their mechanism of action(share). The metformine decreases the glycemia but also"""""""""""""""" inhibits the lipolyse"""""""""""""""""""", reducing free fatty acids and decreasing the production of LDL. We know that the metformine improves the sensibility in the insulin of the muscle and the liver, decreases the hepatic production of glucose, via the néoglucogenèse and increases the peripheral use of the glucose. Effects on the receiver of the insulin were also reported. However the exact mechanism of the effect of the metformine remains dark. \rDans a recent article of J Clin Invest, authors bring solid arguments to think that the target of the effects of the metformine is the kinase protein

[tbombz]

sounds like it was written by someone who thinks they know more than they do. metformin has never been shown to increase insulin sensitivity in muscle. its THOUGHT that this is what it does, because when its used iot appears this way, but taking into account all of its other actions, mainly slowing hepatic production of glucose, there is no reason to believe it has the insulin sensitizing effect as well.

[bea]

inhibits the lipolyse

I SPEAK ABOUT THIS BRO
BEA

[beard]

I have tried metformin 850mg per day for 2 months. I didn't gain any muscle or lose any fat. I took it by itself. Maybe you'll get better results if you combine it ....