Negatives give a extra boost to any workout. As Wes said, certain movements do need a couple of workout partners on the ready. Like benches, inclines, tricep or bicep exercises, overhead presses, etc.
Using negatives for a guy who is weak in chins/pullups can add strength to that exercise when done the normal way. Stand on a box and just lower yourself down with control. Add weight as you progress from workout to workout. Might surprise yourself as to how strong you really are.
Can use negatives with lateral or even front raises. Just press a pair of DB's overhead (10lbs or so above what can be done with in normal raises) and lower them slowly and in control , to the sides or front of the body.
With negatives in a workout, always include the regular version (positive) of the exercise your are doing also. Usually first, getting the body accustomed to a heavier work load. Can get to use 100lb+ in some compound exercises than you normally do. Makn reason for a couple of alert guy's to spot you. Sometimes one guy is never enough.Good luck.