Actually you do not want to hit failure of each set of GVT (10X10's= 100 reps). You do want to activate the same motor units/muscle response using the same exercise (BP for example). Failure is not the option, far from it. A lighter weight is used during the whole 10 sets directed towards the muscle tissue. So as to not overload the joints, tendons, ligaments, etc. Want to focus on the muscles and not stress the joints, etc. etc, etc.. The last few sets,with a much lighter weight, is going to seem very heavy and will work the muscles very strongly. That's what most BB'ers want to do anyway.
Thought LatsMcGee has an interesting idea, it would be more like an extended Giant set rather than a pure form of GVT. He would be hitting the same muscle group but from totally different angles (bp, inclines, declines, flys, cable crossovers,etc). Might be a good idea in the long run. So if LatsMcGee would like to try that form of Giants sets than let us all know the results after 4 to 6 weeks.
Might consider upping the pace of the workout by resting from 60 to 90 seconds between sets. Probably would only want to do one cycle of this style workout to insure proper recovery abilities. Good Luck.
Side Bar: GVT is one of my favorite forms of training after a training cycle of heavy PR/partials workouts. Direct target for the muscles themselves, resting the joints, tendons, etc. Quite a few men, for example, have improved their bench very well when going back to their regular workout protocols after GVT. Works great for squating/DL's also. It's the recruitment of those motor/impulse units that seem to do the trick. 100 good reps per single exercise for a muscle group.