Fools! The answer is the Simpsons.
That 'toon has been on for more than 15 years. It is very smartly written with humor that can appeal to kids in primary school all the way up to university faculty members. A third of the humor on the show probably goes over your head while another third appeals to an audience much younger than you so you miss those jokes too.
With a rich cast characters so varied that everyone can identify with someone on the show the Simpsons towers over the competition.
The show has and continues to have a long list of guest star voices with everyone from Michael Jackson, to Elizabeth Taylor, Oprah Winfrey to members of the Rolling Stones.
Unlike most cartoons the Simpsons has truly evolved over time. Bah!
Doom approves.