Ok...at the request of a mod here, I'm going to tell you guys a bit about the new Fat Burner I'm coming out with.
It's called "PyroGenX" and is part of the "Anthony Roberts" line of supplements produced by Protein Factory.
It primarily works by Mitochondrial Uncoupling, via UCP1 (though there is UCP2 & UCP3 action as well). Think of it like a nutritional version of DNP, which comes from naturally occuring sources. The primary ingredient is Fucoxanthin*. I've also added some other stuff I think is good, but you're probably only interested in the Fucoxanthin.
The dose I'm putting in PyroGenX is 500mgs/cap. And they're going to be bad ass liquid-caps, so they get totally absorbed, 100%. Anyway, in the study I have (thirty fucking bucks to buy the thing!), it shows that in the test animals, a 2% fucoxanthin rich diet (1-2 caps with each meal will get you there), the animals in the test group ended up with 15% less bodyweight and a 25% reduction in abdominal fat.
So I thought this would be a great product, contacted Protein Factory, and it's in production right now. Should be available by the end of this week or next.
Anyway, here's the abstract of the study which shows Fucoxanthin to do what I was just talking about:
Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K.
Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.
Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in rats and mice by feeding lipids from edible seaweed, Undaria pinnatifida. Clear signals of UCP1 protein and mRNA were detected in WAT of mice fed the Undaria lipids, although there is little expression of UCP1 in WAT of mice fed control diet. The Undaria lipids mainly consisted of glycolipids and seaweed carotenoid, fucoxanthin. In the fucoxanthin-fed mice, WAT weight significantly decreased and UCP1 was clearly expressed in the WAT, while there was no difference in WAT weight and little expression of UCP1 in the glycolipids-fed mice. This result indicates that fucoxanthin upregulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight.
PMID: 15896707 [PubMed - indexed for MEDLINE]
