The action of androgens in target cells depends on:
The amount of steroid which can penetrate into the cells,
The extent of metabolic conversation within the cells,
The interactions with receptor proteins and finally,upon the action of androgen receptors.
For a detailed discussion of the production, metabolism, transport and action of androgens, see the book The Leydig Cell edited by A.H.Payne, M.P. Hardy and L.D. Russell (1966).
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