Semorelin

[abc123]

Is anyone familiar with Sermorelin?  From what I understand it is to the pituitary as HCG is to the testes.  But, I really can't find too much on effectiveness or dosage.

[abc123]

To clarify, it stimulates the body to release GH.

[trab]

THere are HGH releasers in the Pharma. There is also many a scam in the suplement catalogs.
Know Pharma from FRAUD. Ive no experience with that stuff, it could be real.

[abc123]

this is us pharma human grade

[trab]

I think the pitutary has like 20+ GRAMS of HGH it hoards. These drugs are powerfull.
Im afraid of them.

[Arnold jr]

If you're looking to release more HGH, buy some HGH...do not over complicate things.

[Arnoldwanabe]

I talked to my doc and he explained it as "persuading" the pituitary gland into producing Gh whereas supplementing with GH shuts you down.  It will not make you produce alot thought.  He said it will make you produce amounts a 20 year old would have, therefore it is used just for anti-aging purposes and not bodybuilding.

[trab]

I talked to my doc and he explained it as "persuading" the pituitary gland into producing Gh whereas supplementing with GH shuts you down.  It will not make you produce alot thought.  He said it will make you produce amounts a 20 year old would have, therefore it is used just for anti-aging purposes and not bodybuilding.

WOW, I cant believe a regular Doc would say that.
Is it a HRT clinic?

[Arnoldwanabe]

Yes he is a doc at an anti-aging clinic.  I asked about Gh and he said it is to hard to justify its use but with this there is more flexibility.   

[trab]

Yes he is a doc at an anti-aging clinic.  I asked about Gh and he said it is to hard to justify its use but with this there is more flexibility.   

THe deal is they just pulled most the HGH form circulation and he's still got that Gh releaser.
HRT Dr Guy dont have your best interest in mind. BMW payments are on his. I'd Ask for testo, its safer.

Id ask RDW or FreakFestMd about this drug. Im not sold on the safety.
THis will prolly be a new push by the HRT's     $$$$$$$4Dr.  Who knows WTF 4 You?

Put it this way, dudes been using testo for decades safely, what about theis Gh releaser? You want2 be guinie pig?

[Arnoldwanabe]

Oh I definately agree with the test. Already have a script for that.  I was just probing him for info and "extras".

[Captain Equipoise]

Bahh...just do some GHB,  all the GH release you could ever want!

[freakfestMD]

Id ask RDW or FreakFestMd about this drug. Im not sold on the safety.

Sermorelin is a Gonadotropin-releasing hormone (GnRH) analog. "Official" name is GhRF 1-29 NH2-acetate. 

I don't have any direct experience with it, but it was originally marketed for children with GH deficiency, including some of the GH-deficiency syndromes that I deal with in my clinical practice.  It was withdrawn from the market by the manufacturer because it just couldn't compete with recombinant GH (rHGH).

Paradoxically, it failed in children for the very reason that makes it a better alternative for GH-replacement therapy (GHRT) in adults.

Its effects are regulated at the level of the pituitary gland, stimulating pituitary gene transcription of human growth hormone messenger RNA (hGHmRNA) and thereby increasing pituitary GH reserve.  Pituitary recrudescence resulting from Sermorelin helps slow the cascade of hypophyseal hormone failure that occurs with normal aging.  It's mode of action helps avoid some of the health concerns of rHGH.  Most specifically, tissue exposure to GH released by the pituitary under the influence of sermorelin is "episodic," rather than so-called "square-wave."  So what does this mean?

"Square-wave" release refers to what occurs with the pharmacologic presentation of exogenous hormone as a bolus (i.e. one good shot in the old thigh), and is not controlled by normal feedback mechanisms--therefore when one injects standard Chinese-made GH, tissue exposure to elevated GH concentrations is persistent and eventually may lead to tachyphylaxis and reduced efficiency.  "Episodic" release prevents tachyphylaxis by mimicking more normal pulsatile release and physiology.

And now for the kicker for anti-aging clinics:  Unlike GH, the off-label prescribing of sermorelin is not (yet ) prohibited by federal law.

[trab]

Thanks Freak    I can also allways understand your stuff...
The pulsatiave thing is interesting.
 
Im not sure of this stuffs price, But I also like to let other people be new pharma Guinie pigs for a decade or so.
It just makes me feel better.

But, I got no Idea how long this stuff has been in use, or how widely prescribed.

[bhdvette]

Freakfestmd is 100% correct at what he says. I have been monitored by my doc who specializes in anti aging. He has managed and guided me through my therapy and training. At 49 years old I am now again feeling like a 22 year old kid. Only using testosterone for four months now, I have enjoyed every second at the gym and have lost right at 50lbs of fat. I went from 269 down to 219! from bursting out of 48's now into 36's.. It feels great to go to the gym again. At least now again, like I did at 22 I can see results from the hard work at the gym. Great news, my insurance even pays for it, its a deficiency in my body and is medically justified. Next will be Semorelin. This will not be payed for by my insurance, it's considered to be for comedic purposes. With a script from my doc it will cost me about $450 for an 8 month supply.
Amazing, I have recommended 4 guys to ask there doc to check there tes level, and all four have now been prescribed tes.   

[DIVISION]

THe deal is they just pulled most the HGH form circulation and he's still got that Gh releaser.
HRT Dr Guy dont have your best interest in mind. BMW payments are on his. I'd Ask for testo, its safer.

Id ask RDW or FreakFestMd about this drug. Im not sold on the safety.
THis will prolly be a new push by the HRT's     $$$$$$$4Dr.  Who knows WTF 4 You?

Put it this way, dudes been using testo for decades safely, what about theis Gh releaser? You want2 be guinie pig?

I agree with Trab, he's experienced with HRT docs.

For what you actually get, I don't think the price is cost effective.

I am the type of guy who would dictate to the doctor what I'd want prescribed and if he didn't agree, I'd walk and find another doc.

I have dropped family practice docs in the past in favor of endocrinologists for this reason.

I want to deal with someone who will work with me, and take direction.........

Remember, you are paying the doctor.

If he won't take direction in terms of meds and scripts, there are other docs who will.   



DIV

[abc123]

I agree with Trab, he's experienced with HRT docs.

For what you actually get, I don't think the price is cost effective.

I am the type of guy who would dictate to the doctor what I'd want prescribed and if he didn't agree, I'd walk and find another doc.

I have dropped family practice docs in the past in favor of endocrinologists for this reason.

I want to deal with someone who will work with me, and take direction.........

Remember, you are paying the doctor.

If he won't take direction in terms of meds and scripts, there are other docs who will.   



DIV

I am very familiar with HRT clinics.  There are plenty that will prescribe much more test, etc. than you would think.  For example, 500mg Test EW, 50 mg Stanzolol EOD, and 400 mg of Deca EW.   And, insurance covers it all if you have good insurance and diagnosed low tesosterone levels.  Plus my doc has me on GH, Thyroid and some other stuff.