Here's the first 2 pages of the book:
Justin,
How exactly does fat loss occur in the body? Are there hormones or enzymes that do this? Is this how ‘fat burners’ work? ________________________ ________________________ ______
Fat loss is the physiologic process of Lipolysis. Lipolysis is the breakdown of the fat stored in fat cells. This causes the release of fatty acids into the bloodstream to circulate through the body. Ketones are also produced in this process.
Lipolysis is induced by:
Epinephrine: “adrenalin,” both a hormone and a neurotransmitter.
Norepinephrine: Same as epinephrine, minus a methyl group.
Glucagon: Opposite of insulin. A hormone that causes glycogen to be released.
Adrenocorticotropin Hormone (ACTH): Released from the pituitary gland in response to stimuli.
All of these increase cAMP production.
cAMP activates Protein Kinase A.
Protein Kinase A activates Lipases.
Lipase: Main enzyme responsible for breaking down fats in humans.
cAMP is a second messenger, involved in signal transduction. It is necessary for hormones like glucagon and adrenalin (epinephrine and norepinephrine) to permeate cells.
When these fatty acids are released into the bloodstream, they can then be used for energy production by the body.
Justin,
In your recent article, “The Fat that Burns Fat,” you were talking about GLA (linoleic acid) as a supplement. I currently use CLA (conjugated linoleic acid) as a supplement and on face value it looks like it’s derived from the same sort of thing. Are GLA/CLA essentially the same thing?
The reason I ask is that one is a reasonably expensive supplement and the other is a lot cheaper product from a health store.
CLA is a different product.
CLA is actually a trans fat.
Much of the recent evidence on CLA shows little benefit to healthy, exercising people in regards to body fat loss.
GLA, or gamma-linolenic acid, is a derivative of Omega 6 fatty acids, which are essential to human life.
Linoleic acid, as you have written in your question, is different than GLA, although still an Omega 6 fatty acid.
Arachidonic acid, another derivative of Omega 6 fatty acids, is one of the most potent growth regulators of the body.
Omega 6 fatty acids are inflammatory and growth promoting.
I'm not a huge fan of CLA...although I feel the jury is still out on its benefits.