I think to get cartoonishly big you would need to find the most select of the gene pool in regards to hormone response which is unlikely since bbing as a whole isn't that popular in respects to getting to the pro level. Second more doesn't equal better in terms of drugs. Some designer shit that puts you in the realm of cattle would need to be created. I also think the joints are taxed to the max at Colemans size and anything much bigger can't be sustainable for any amount of time (+10 years)
true, ud need the muscles to look full and round, ala serge nubret, arnold, kevin levrone, etc. but most of the top pros today do have very cartoonish size and shape. dexter, melvin, dennis, jay to a point, ronnie, etc. the judges have dictated that shape combined with size will be the ultimate winner (in a fair world), so if there are top bbers who can reach the pro size and are blessed with great fullness and shape, we'll likely see them at the arnold and olympia. theyre rare, but theyre out there, and theyve done well (ala oliva, wolf and coleman, to name a few of the freaks.)
ud know more about the drugs than i do, but i agree, a new formula would probably need to be created to really help the weight increase and make it 'easier' to get to that next level of size