Herpes Simplex Type-I, possible cure

[warrior_code]

Up until recently there has been no cure for this virus, only topical, mechanical and oral treatments which can lessen the severity of the symptoms.  Research done at the U of Florida may change all this.  They have developed a hammerhead Ribozyme which cleaves key genes in the HSV-1 virus, causing it to lose it's ability to replicate.  This novel idea has been shown to be a success on studies done on rabbits as well as in cell culture.  This could very well be a cure for the previously thought to be incurable virus.   Below is a link to the nature paper published in 2006, which reported these findings.
 
http://www.nature.com/mt/journal/v13/n1s/abs/mt2006942a.html
http://apps.rgp.ufl.edu/otl/viewTechInfo.cfm?case=10994

I am creating this thread in order to raise awareness to the research that is being conducted at the University of Florida.  The more people that realize these novel methods of molecular therapy being developed which can potentially cure this virus, the sooner this treatment will be available and potentially provide a life long solution to those who suffer from cold sores. They are having trouble with funding as this breakthrough technology is not well know, the more people that know about it, the better.

Thank you

[m8]

ok

[JohnnyVegas]

Yes, we all know that everything that works on a "rabbit" automatically works on humans, becasue the physiology is so similar.

 

[240 is Back]

Do not kiss a girl unless you have known her for a bit and know she's not a total whore.

If you do plan on running with whores, use them at your own risk, but you don't kiss them.  Tell them you have a cold or something.

Also about 80% of the tricks you see in club have HPV, which condoms cannot stop and is skin-to-skin contact.  You getbiggers have to be careful.  Many girls are dirty!  Go pick up some librarian girls and train them yourself, much safer.

[stormshadow]

Do not kiss a girl unless you have known her for a bit and know she's not a total whore.

If you do plan on running with whores, use them at your own risk, but you don't kiss them.  Tell them you have a cold or something.

Also about 80% of the tricks you see in club have HPV, which condoms cannot stop and is skin-to-skin contact.  You getbiggers have to be careful.  Many girls are dirty!  Go pick up some librarian girls and train them yourself, much safer.

The majority of people get HSV-1 in their childhood.

[TrueGrit]

Don't get it..that's my advice.

[240 is Back]

The majority of people get HSV-1 in their childhood.

don't play spin the bottle at recess?

[Bast000]

don't play spin the bottle at recess?

are you saying you have played spin the bottle and made out with a dude, 240?

[BroadStreetBruiser]

Herpes are a badge of honor in most rust belt cities.

[240 is Back]

are you saying you have played spin the bottle and made out with a dude, 240?

in cleveland we played spin the glock.

[Camel Jockey]

Finally, a topic that Derek Anthony will read with his full attention span.

[warrior_code]

with all the dreaded diseases in the world.......... herpes simplex ? 


NT

Herpes Simplex Keratitis is the leading cause of corneal blindness in the developed world.  No doubt there are much more harmful diseases that need more attention.  Keep in mind, having a herpes simplex virus can increase ones chances of contracting hiv, as well as other harmful ailments, especially in immunocompromised individuals.  When you look at this from a holistic perspective, only good can come from it.   These novel findings can also act as a catalyst to spark other treatments which use the principles of molecular therapy to cure/treat other ailments. 

[Marty Champions]

every hoe has a unique disease


you develop new dna and NEW ANTIBODIES, so you get sick some disease sideffect noticable or unnoticable

but a good diet such as the ascension diet takes care of all things

the lower conscious 'group' of people will resort to pills or pure madness and suffereing if they were to get a disease

a disease that shows through the skin is your inner reptilian coming out, it comes out because you are simply not giving it some type of food it wants and needs thus the disease or reptilian will show its 'face' to remind you that you are fucking up and better do something about it, you either make a choice to actively change your lifestyle working out more or better diet so the reptilian can sleep within. most diseases of this sort is INFLAMATION, any grain based high processed sugar or processed protien powder diet will give you inflamation thus the reptilian is inflamed and comes out. if you are treating 'it' badly with a shitty diet and a shitty lifestyle expect the reptilain within to be very pissed off

[benchthis]

Up until recently there has been no cure for this virus, only topical, mechanical and oral treatments which can lessen the severity of the symptoms.  Research done at the U of Florida may change all this.  They have developed a hammerhead Ribozyme which cleaves key genes in the HSV-1 virus, causing it to lose it's ability to replicate.  This novel idea has been shown to be a success on studies done on rabbits as well as in cell culture.  This could very well be a cure for the previously thought to be incurable virus.   Below is a link to the nature paper published in 2006, which reported these findings.
 
http://www.nature.com/mt/journal/v13/n1s/abs/mt2006942a.html
http://apps.rgp.ufl.edu/otl/viewTechInfo.cfm?case=10994

I am creating this thread in order to raise awareness to the research that is being conducted at the University of Florida.  The more people that realize these novel methods of molecular therapy being developed which can potentially cure this virus, the sooner this treatment will be available and potentially provide a life long solution to those who suffer from cold sores. They are having trouble with funding as this breakthrough technology is not well know, the more people that know about it, the better.

Thank you

everyone has type I they should be working on type II

[Jake_W]

 

[Parker]

So, finally there might be an end to those stupid Herpes commercials...

[Rami]

The right kind of fats and plenty of them will fight and eliminates viruses.

"Some of the viruses inactivated by these lipids are HIV, measles virus, herpes simplex virus-1 (HSV-1), herpes simplex virus-2 (HSV-2), vesicular stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV). Many of the pathogenic organisms reported to be inactivated by these antimicrobial lipids are those known to be responsible for opportunistic infections in HIV-positive individuals. In addition to viruses, several bacteria and fungi have also been reported to be suppressed by monolaurin and coconut oil."

But it doesn't have to be coconut oil. Most natural oils, Preferable mono unsaturated oils and saturated naturally occurring fats.

polyunsaturated oils like vegetable oils (corn oil etc) are not good, they increase infection responses, raise your estrogen to testosterone ratio. lower your cholesterol even the very useful healthy kind. There have been a long ongoing brainwash to eat high carb low fat and polyunsaturated vegetable oils for a long time. All that does is increase your risk for diabetes and many other disorders. It all has to do with selling grains and profit. Corn and Soy lowers your thyroid function. That is why they feed animals this, it makes them fat in no time so it is very cheap.

[TechnoViking]

Most non deadly Virus's are shit that just about everyone will get in there lifetime...Its the radical right that has been pushing there agenda for decades in using scare tactics so people stop having sex...

Like the war on drugs, these tactics are a FAIL...Who gives a flying fuck if you get a virus that your body will eventually build up antibodies for...Its evolution at work...

[ATHEIST]

Yes, we all know that everything that works on a "rabbit" automatically works on humans, becasue the physiology is so similar.

 

 Thats how the majority of anit-viruses and venoms are perfected you moron.

[warrior_code]

everyone has type I they should be working on type II

I would imagine if this treatment is a success, something similar would work for type II as well, their genomes are very similar.  There actually is a vaccine currently being tested now for herpes simplex type II under Dr David M. Knipe, from Harvard.  It is however much different from what I posted. 

Parker, it is funny you mention that.  I believe the reason this treatment has not been licensed yet(It has been around for a while) is because Pharmaceutical companies have no interest in it.  Why offer a life long cure when you can keep on making profit off temporary  measures?  There are obviously other factors involved, but above all they are a corporation whose prime concern is profit. 

[ATHEIST]

Like the war on drugs, these tactics are a FAIL...Who gives a flying fuck if you get a virus that your body will eventually build up antibodies for...Its evolution at work...

 your body doesnt build antibodies for everything. and why would the "right" want people to stop having sex? there is huge money to be made with pharma companies.

[theworm]

Up until recently there has been no cure for this virus, only topical, mechanical and oral treatments which can lessen the severity of the symptoms.  Research done at the U of Florida may change all this.  They have developed a hammerhead Ribozyme which cleaves key genes in the HSV-1 virus, causing it to lose it's ability to replicate.  This novel idea has been shown to be a success on studies done on rabbits as well as in cell culture.  This could very well be a cure for the previously thought to be incurable virus.   Below is a link to the nature paper published in 2006, which reported these findings.
 
http://www.nature.com/mt/journal/v13/n1s/abs/mt2006942a.html
http://apps.rgp.ufl.edu/otl/viewTechInfo.cfm?case=10994

I am creating this thread in order to raise awareness to the research that is being conducted at the University of Florida.  The more people that realize these novel methods of molecular therapy being developed which can potentially cure this virus, the sooner this treatment will be available and potentially provide a life long solution to those who suffer from cold sores. They are having trouble with funding as this breakthrough technology is not well know, the more people that know about it, the better.

Thank you

Dumbass!  Acyclovir/Valtrex also kills the virus, killing of the virus is not the issue. It replicates in the nerves where no systemics get to.  So once you have it, there is no cure, despite what those clowns in Florida are saying.

anyway, 90% of the population has HSV-1 antibodies, so what? 

Thanks for the "awareness," assclown.

[Parker]

I would imagine if this treatment is a success, something similar would work for type II as well, their genomes are very similar.  There actually is a vaccine currently being tested now for herpes simplex type II under Dr David M. Knipe, from Harvard.  It is however much different from what I posted. 

Parker, it is funny you mention that.  I believe the reason this treatment has not been licensed yet(It has been around for a while) is because Pharmaceutical companies have no interest in it.  Why offer a life long cure when you can keep on making profit off temporary  measures?  There are obviously other factors involved, but above all they are a corporation whose prime concern is profit. 

I agree, it is not financially beneficial right now for a long term cure. WHen more and more people have, then maybe. It's kinda like making chewing gum that last longer. If it last longer, will people pay for more, or if the good taste leaves quickly, would people buy more, just to keep the taste going?

[warrior_code]

Dumbass!  Acyclovir/Valtrex also kills the virus, killing of the virus is not the issue. It replicates in the nerves where no systemics get to.  So once you have it, there is no cure, despite what those clowns in Florida are saying.

anyway, 90% of the population has HSV-1 antibodies, so what? 

Thanks for the "awareness," assclown.

Hi,

I suggest you first study and find out what a ribozyme is, specifically a hammerhead(that is if you do not know).  You are correct, the virus does lay dormant in the nerve ganglia.  Valtrex and the other current treatments will lesson the severity and reduce the healing period of an outbreak.  They do not prevent it from re-occuring.  The presence of antibodies usually will lesson the amount of outbreaks one has as well as the severity of them no doubt.  This is the logic behind the HSV-2 vaccine I mentioned above which seeks to induce a VERY strong immune response by using a live strain of HSV-2 with a few genes deleted from it. 

 This novel method on the other hand utilizes defective forms of HSV-1 which serve as vectors to transport the ribozyme to cells which function in sustaining the infection.  Then the hammerhead cleaves onto certain key genes involved in replication.  This treatment can potentially stop all re-occuring outbreaks,  by virtue of the virus not able to replicate.     

[theworm]

I know what a ribosome is dumbass, but it is not relevant.  That is not a cure, still lays dormant and can be reactivated. 

Sounds like you are some college student, and recently read an article 2 years old.

bottom line is HSV-1 is not a major health problem, 90% of people have it, and its not a big deal. 

bigger news is the HPV-vaccine.  thats the biggest news in virology in the past 10 years---at least that prevents cancer!