Author Topic: weight based dosing?  (Read 1877 times)

theworm

  • Getbig V
  • *****
  • Posts: 4019
  • Getbig!
weight based dosing?
« on: August 01, 2008, 03:08:07 PM »
i was taking 300 deca and 300 test and only gained a solid 10 so far (week 7).  i know my diet is not up to par, but you think being 235 (low body fat, its just cause i am 6'4) pounds makes a difference?

you think its the same as a 170 pounder taking 150 test and 150mg deca?

should i calculate my dosages based on me being bigger? 
you are gay.

candidizzle

  • Getbig V
  • *****
  • Posts: 9046
  • Trueprotein.com 5% discount code= TRB953
Re: weight based dosing?
« Reply #1 on: August 01, 2008, 06:37:32 PM »
ummmmmmm

well

more muscle = more androgen receptors
more androgen receptors = more effective your androgens will be

so

that would lead me to believ that

more muscle = more effective your androgens would be


so maybe youve got it baqckwards... maybe a 170 lber taking 300 t + 300 nd  would be the same as a 235 lber taking 150 t + 150 nd ....

maybe

speculation at its finest ! LOL

OTHstrong

  • Competitors II
  • Getbig V
  • *****
  • Posts: 14122
  • Jasher
Re: weight based dosing?
« Reply #2 on: August 01, 2008, 07:29:00 PM »
i was taking 300 deca and 300 test and only gained a solid 10 so far (week 7).  i know my diet is not up to par, but you think being 235 (low body fat, its just cause i am 6'4) pounds makes a difference?

you think its the same as a 170 pounder taking 150 test and 150mg deca?

should i calculate my dosages based on me being bigger? 
I understand that its always a wise decision to be carful about how many mg per week to take, simply take the minimum if you are unsure, however in your case the saying `` you must guard against being to conservative``applies.. You are a big man with a big frame and your natural hormone levels are probably slightly higher then that of the average person. In your particuler case I would advise you to double your test intake for the remainder of your cycle duriation.

Vet

  • Getbig IV
  • ****
  • Posts: 1679
  • Immortal
Re: weight based dosing?
« Reply #3 on: August 01, 2008, 08:17:42 PM »
This is something I've struggled with and struggled with in comparing human medicine to veterinary medicine.  In veterinary medicine, all animals are dosed based on the mass (kg "weight") of the animal.  Scaling is used to in veterinary medicine to provide doses based on mass even in very large animals. 


In human medicine it seems much more like its an adult/child dosing with many different medications (antihistamines, antibiotics, certian blood pressure medications, etc).  Just as an example: I'm a 300+ lb man.  If I get an ear infection and I get the same cipro prescription my 132 lb wife gets.  It doesn't make much sense.   

theworm

  • Getbig V
  • *****
  • Posts: 4019
  • Getbig!
Re: weight based dosing?
« Reply #4 on: August 02, 2008, 05:36:42 AM »
i agree, if i am twice the size as a normal person, i think i would need double the medicine.  Its all about distribution of the medicine, breakdown, etc.   
you are gay.

candidizzle

  • Getbig V
  • *****
  • Posts: 9046
  • Trueprotein.com 5% discount code= TRB953
Re: weight based dosing?
« Reply #5 on: August 02, 2008, 11:25:45 AM »
more muscle = more androgen receptors
more androgen receptors = more effective your androgens will be


well these two premis are fact.


and that being the case, i dont know why this conclusion =

more muscle = more effective your androgens would be

wouldnt be fact as well.




OTHstrong

  • Competitors II
  • Getbig V
  • *****
  • Posts: 14122
  • Jasher
Re: weight based dosing?
« Reply #6 on: August 02, 2008, 11:29:11 AM »
more muscle = more androgen receptors
more androgen receptors = more effective your androgens will be


well these two premis are fact.


and that being the case, i dont know why this conclusion =

more muscle = more effective your androgens would be

wouldnt be fact as well.




Candi stop with all the thechnocal non-sense, his question was does he need more or would he benefit from more and the answere in his case is yes, what you say is true, but why not keep it in simple terms where people that don't know much can understand.

candidizzle

  • Getbig V
  • *****
  • Posts: 9046
  • Trueprotein.com 5% discount code= TRB953
Re: weight based dosing?
« Reply #7 on: August 02, 2008, 11:32:57 AM »
of course he will benefit from more mg.


but his question was on the subject of weight based dosing, not whther more steroids would work better.



vet and worm both said they think that a certain mg of AAS  would work better in a smaller lighter perso than it would in a bigger heavier person.


im not so sure thats the case.


OTHstrong

  • Competitors II
  • Getbig V
  • *****
  • Posts: 14122
  • Jasher
Re: weight based dosing?
« Reply #8 on: August 02, 2008, 11:38:40 AM »
of course he will benefit from more mg.


but his question was on the subject of weight based dosing, not whther more steroids would work better.



vet and worm both said they think that a certain mg of AAS  would work better in a smaller lighter perso than it would in a bigger heavier person.


im not so sure thats the case.


Not in every case, but assuming all varibles are the same why wouldn't this be true.

Vet

  • Getbig IV
  • ****
  • Posts: 1679
  • Immortal
Re: weight based dosing?
« Reply #9 on: August 02, 2008, 11:42:23 AM »
of course he will benefit from more mg.


but his question was on the subject of weight based dosing, not whther more steroids would work better.



vet and worm both said they think that a certain mg of AAS  would work better in a smaller lighter perso than it would in a bigger heavier person.


im not so sure thats the case.


::)

No, thats not what I said.  I said that it makes more sense for drugs to be dosed based on mass of the patient.  This means a smaller mass individual would require a smaller dose of a given drug to have the same effect while a larger mass individual would require a higher dose.  Worm brought up what I was thinking with volume of distributions, metabolism of the drug, ect.

The drugs don't "work better" in smaller vs larger individuals.  ::)  

candidizzle

  • Getbig V
  • *****
  • Posts: 9046
  • Trueprotein.com 5% discount code= TRB953
Re: weight based dosing?
« Reply #10 on: August 02, 2008, 12:03:15 PM »
This means a smaller mass individual would require a smaller dose of a given drug to have the same effect while a larger mass individual would require a higher dose.


that is what i said you said

and i said i dont think thats the case, i this instance.


Vet

  • Getbig IV
  • ****
  • Posts: 1679
  • Immortal
Re: weight based dosing?
« Reply #11 on: August 02, 2008, 07:27:52 PM »
This means a smaller mass individual would require a smaller dose of a given drug to have the same effect while a larger mass individual would require a higher dose.


that is what i said you said

and i said i dont think thats the case, i this instance.




why?

candidizzle

  • Getbig V
  • *****
  • Posts: 9046
  • Trueprotein.com 5% discount code= TRB953
Re: weight based dosing?
« Reply #12 on: August 02, 2008, 07:52:05 PM »

why?
because..=
more muscle = more androgen receptors
more androgen receptors = more effective your androgens will be


well these two premis are fact.


and that being the case, i dont know why this conclusion =

more muscle = more effective your androgens would be

wouldnt be fact as well.





i agree with onetime hard, he would benefit from increasing the doseage. but NOT because he has more body mass.

S_Samuel

  • Getbig III
  • ***
  • Posts: 514
Re: weight based dosing?
« Reply #13 on: August 03, 2008, 01:41:06 PM »
Base dosages off of LEAN mass. Better to base off amount of muscle rather than amount of weight.

Vet

  • Getbig IV
  • ****
  • Posts: 1679
  • Immortal
Re: weight based dosing?
« Reply #14 on: August 03, 2008, 06:04:59 PM »
because..=
i agree with onetime hard, he would benefit from increasing the doseage. but NOT because he has more body mass.

Yes, but if he has more muscle mass, he'll have more overall body mass.  You are getting caught up in technomumbojumbo that almost looks like you are having a real hard time conceptualizing.