I've ran 100mg ED x 5 days a week, and had bad sides. I've had best luck with 75mgs ED for 7 days, and then 75mgs EOD for 7 Days, and back and forth. I rotate all injection sites, Shot one and two in Glute, Three and Four in Quad, and five and six in Delts. I hate shooting in the Delt though. It hurts so bad.